Orofacial cancer and its treatment can produce disfigurement, serious deficits in speech and numerous problems related to food and airway management. Preliminary research has demonstratad that a prosthetic approach to patient rehabilitation may lead to significant improvements in some or all of these areas. Namely, an artifical tongue specifically designed to improve speech and food management in a total glossectomy patient lead to a 25-30% improvement in the patient's conversational speech intelligibility, and eliminated the need for tube feeding. Further research which incorporates and elaborates the principles of speech analysis used in designing the prosthetic tongue could lead to improved speech in other orofacial cancer patients. In this research project, a small number of patients with total or partial glosssectomy, unilateral maxillectomy or more extensive unilateral facial excisions will be subjected to detailed speech and dental evaluations by a speech pathologist and a maxillofacial prosthodontist, respectively. Based on these evaluations, prosthetic appliances which enable each patient to more closely approximate normal vocal tract dynamics and/or acoustics during speech will be designed and fabricated. Analyses of the prostheses' effects on each patient's speech will be followed by revisions in prosthesis design when the data indicate further improvements in speech may be possible. Specific prosthesis variables to be investigated, in addition to size/shape parameters, include type of fabrication material utilized, and whether the prosthesis is solid or hollow. Results of the study are expected to provide information useful to refining and expediting the design of speech prostheses in selected orofacial cancer patients. Further, results will provide a data base critical to a larger-scale investigation into speech characteristics and the potential of prosthetic rehabilitation in other orofacial cancer patients, computer-implemented techniques of prosthesis design based or """"""""a priori"""""""" acoustic and anatomical information regarding an individual patient and, in the case of glossal prostheses, the potential for a prosthesis capable of limited, active movement.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Small Research Grants (R03)
Project #
5R03DE006799-02
Application #
3424818
Study Section
NIDR Special Grants Review Committee (DSR)
Project Start
1984-01-01
Project End
1985-12-31
Budget Start
1985-01-01
Budget End
1985-12-31
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
Schools of Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618