Neurobiology of Disease in Children Program Announcement: This application is in response to PA-13-347 this proposal requests support for a scientific meeting entitled Neurobiology of Disease in Children (NDC) to be held between the years of 2016-2020. The NDC symposium is organized by Dr. Bernard Maria, Director of Child Neurology & Developmental Medicine, Goryeb Children's Hospital. The NDC Symposium started over 15 years ago as a satellite event to feature important, and often under-represented, topics that were of interest to practicing child neurologists. The NDC symposium is now juxtaposed with the Child Neurology Society (CNS) annual meeting, and its educational role in the field of child neurology is firmly established. Last year, the NDC Symposium attracted nearly 500 of the country's 800 child neurologists; a premier opportunity for child neurologists to exchange ideas with colleagues in the field, to learn about the latest research and treatment strategies for specific neurological disorders, and to explore ways for practice improvement. In 2016-2020 symposium topics will include: neurofibromatosis - type I and II, leukodystrophies, brain tumors, Tourette syndrome, and traumatic brain injury. The NDC symposia uniquely serves and educates the child neurology community, ensuring clinicians can be most effective at the bedside, while also contributing to discussions on future research directions.

Public Health Relevance

This application describes our plan for the continuation of symposia titled, Neurobiology of Disease in Children (NDC), to be held in conjunction with the 2016 to 2020 annual Child Neurology Society (CNS) meetings. In 2016 - 2020 symposium topics will include: neurofibromatosis - type I and II, leukodystrophies, brain tumors, Tourette syndrome, and traumatic brain injury; clinical conditions that practicing child neurologists encounter on a weekly basis. Moving forward, we plan to stay true to the established role of the NDC in the field of child neurology; which is to say, we plan to bring together clinicians, scientists, caregivers and NIH program officers to determine how recent findings in child neurology can be translated to enhance clinical understanding and affect clinical practice.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Conference (R13)
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National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
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Vivalda, Joanna
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Atlantic Health System, Inc.
United States
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Nariai, Hiroki; Duberstein, Susan; Shinnar, Shlomo (2018) Treatment of Epileptic Encephalopathies: Current State of the Art. J Child Neurol 33:41-54
Maria, Bernard L (2017) Epileptic Encephalopathy. J Child Neurol 32:342-343
Germain, Blair; Eppinger, Melissa A; Mostofsky, Stewart H et al. (2015) Recent Advances in Understanding and Managing Autism Spectrum Disorders. J Child Neurol 30:1887-920
Maria, Bernard L (2015) Autism Spectrum Disorders: Current Understanding and Future Directions. J Child Neurol 30:1859-60
Area-Gomez, Estela; Schon, Eric A (2014) Mitochondrial genetics and disease. J Child Neurol 29:1208-15
Li, Minghui; Bolduc, Aaron R; Hoda, Md Nasrul et al. (2014) The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma. J Immunother Cancer 2:21
Travaglini, Lorena; Brancati, Francesco; Silhavy, Jennifer et al. (2013) Phenotypic spectrum and prevalence of INPP5E mutations in Joubert syndrome and related disorders. Eur J Hum Genet 21:1074-8
Yum, Mi-Sun; Lee, Eun Hye; Ko, Tae-Sung (2013) Vigabatrin and mental retardation in tuberous sclerosis: infantile spasms versus focal seizures. J Child Neurol 28:308-13
Dolisca, Sarah-Bianca; Mehta, Mitali; Pearce, David A et al. (2013) Batten disease: clinical aspects, molecular mechanisms, translational science, and future directions. J Child Neurol 28:1074-100
Maria, Bernard L (2013) Batten disease: current understanding and future directions. J Child Neurol 28:1072-3

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