Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Academic Research Enhancement Awards (AREA) (R15)
Project #
1R15HL050082-01
Application #
2226196
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1993-06-01
Project End
1997-05-31
Budget Start
1993-06-01
Budget End
1997-05-31
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Missouri-Columbia
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
112205955
City
Columbia
State
MO
Country
United States
Zip Code
65211
Jones, J J; Rapps, J A; Sturek, M et al. (1999) Contractile function and myoplasmic free Ca2+ (Cam) in coronary and mesenteric arteries of endotoxemic guinea pigs. Shock 11:64-71
Myers, T P; Myers, P R; Adams, H R et al. (1999) Enhanced prostanoid-mediated vasorelaxation in pulmonary arteries isolated during experimental endotoxemia. Shock 11:436-42
Zhong, J; Adams, H R; Rubin, L J (1997) Cytosolic Ca2+ concentration and contraction-relaxation properties of ventricular myocytes from Escherichia coli endotoxemic guinea pigs: effect of fluid resuscitation. Shock 7:383-8
Adams, H R (1996) Physiologic, pathophysiologic, and therapeutic implications for endogenous nitric oxide. J Am Vet Med Assoc 209:1297-302
Cogswell, A M; Johnson, P J; Adams, H R (1995) Evidence for endothelium-derived relaxing factor/nitric oxide in equine digital arteries. Am J Vet Res 56:1637-41
Myers, P R; Zhong, Q; Jones, J J et al. (1995) Release of EDRF and NO in ex vivo perfused aorta: inhibition by in vivo E. coli endotoxemia. Am J Physiol 268:H955-61
Keller, R S; Jones, J J; Kim, K F et al. (1995) Endotoxin-induced myocardial dysfunction: is there a role for nitric oxide? Shock 4:338-44
Parker, J L; Myers, P R; Zhong, Q et al. (1994) Inhibition of endothelium-dependent vasodilation by Escherichia coli endotoxemia. Shock 2:451-8
Graier, W F; Myers, P R; Rubin, L J et al. (1994) Escherichia coli endotoxin inhibits agonist-mediated cytosolic Ca2+ mobilization and nitric oxide biosynthesis in cultured endothelial cells. Circ Res 75:659-68
Zhong, J; Rubin, L J; Parker, J L et al. (1994) Cardiodynamic response to Escherichia coli endotoxemia: effects of fluid resuscitation. Shock 2:203-9