Chronic low back pain (cLBP) is the leading cause of disability worldwide and is one of the top reasons for seeking healthcare. High-impact low back pain is particularly problematic, defined as chronic pain accompanied by significant restrictions in work, social, and/or self-care activities for six months or more. High-impact pain is associated with greater pain-related disability, opioid use, and healthcare costs compared to pain of lower impact. Thus, efforts to reduce chronic pain impact have become a public health initiative. Low back pain and overweight/obesity are highly comorbid; overweight and obese individuals are up to 43% more likely to have cLBP compared to normal weight individuals. Together, the additive effects of overweight/obesity and chronic pain may play a larger role in increasing the risk for other adverse health-related comorbidities. To understand the relationship between excess weight and pain impact, we have developed a conceptual model that suggests the greatest reductions in pain impact for adults with comorbid cLBP and overweight/obesity will be observed by delivering content aimed at increasing non-food environmental reward and positive affect, in addition to delivering evidence-based weight loss and pain coping treatments. Therefore, the aim of this exploratory study is to examine the feasibility and acceptability of an integrated pain and weight management intervention (EMPOWER) for middle-aged and older adults with moderate-to-high impact low back pain by addressing mechanisms of environmental reward and positive affect. Forty adults (ages 45-80 years) with comorbid overweight/obesity (BMI?25 kg/m2) and moderate-to-high impact cLBP will be assigned to an 8-month intervention, whereby they will receive a group- and telephone-based program featuring integrated behavioral weight loss treatment and cognitive-behavioral pain coping therapy. To address the key mechanisms of environmental reward and positive affect, the proposed intervention will incorporate systematic pleasant activity scheduling and values-clarification techniques. Assessments will be conducted at baseline and at the 4- and 8-month time points. The proposed research will be a step toward the development of therapeutic modalities aimed at improving pain and weight management in adults with comorbid cLBP and overweight/obesity, and will provide essential information to guide a larger, randomized-controlled trial of the EMPOWER intervention.

Public Health Relevance

Chronic low back pain and overweight/obesity are highly comorbid and represent major public health concerns; however, interventions targeting this comorbidity are limited. Therefore, this single-arm pilot study aims to examine the feasibility and acceptability of an integrated pain and weight management intervention for overweight/obese adults with moderate-to-high impact low back pain. Environmental reward and positive affect ? key mechanisms that contribute to pain and excess weight ? will be addressed and represent a novel approach with potential for improving the health of this at-risk population.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21AG070642-01
Application #
10107020
Study Section
Behavioral Medicine, Interventions and Outcomes Study Section (BMIO)
Program Officer
Joseph, Lyndon
Project Start
2021-02-15
Project End
2023-01-31
Budget Start
2021-02-15
Budget End
2022-01-31
Support Year
1
Fiscal Year
2021
Total Cost
Indirect Cost
Name
University of Florida
Department
Dentistry
Type
Schools of Dentistry/Oral Hygn
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611