Osteoarthritis is the most common form of arthritis and affects up to 37% of adults in the United States. The knee is one of the most commonly affected joints, especially among the elderly; knee osteoarthritis inflicts considerable pain, stiffness and limited range of motion, resulting in morbidity and health services utilization. While conventional treatments provide some relief, they are associated with a number of untoward side- effects, including excess mortality from upper gastrointestinal bleeding. Acupuncture has a long history of safe and effective use for a variety of conditions in Asia, and reports of clinical success in patients with osteoarthritis have appeared in recent years. However, efforts to scientifically evaluate its efficacy have been impeded by a number of methodological problems.The protocol for the present study represents the investigator's concerted attempts to resolve some of these problems. The purpose of this study is to measure and evaluate changes in the valid and reliable outcomes of self-reported pain and physical function among patients age 50 and above with osteoarthritis of the knee. The study will be a single- blind, controlled trial with independent assessments, comparing the effects of traditional acupuncture and conventional therapy. Results of this study will provide important data about the usefulness of acupuncture in this common disabling condition.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21RR009327-01
Application #
2284625
Study Section
Special Emphasis Panel (SSS (S4))
Project Start
1994-09-30
Project End
1996-09-29
Budget Start
1994-09-30
Budget End
1996-09-29
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Ezzo, Jeanette; Wright, Katherine; Hadhazy, Victoria et al. (2002) Use of the Cochrane electronic library in complementary and alternative medicine courses in medical schools: is the giant lost in cyberspace? J Altern Complement Med 8:681-6
Ezzo, J; Hadhazy, V; Birch, S et al. (2001) Acupuncture for osteoarthritis of the knee: a systematic review. Arthritis Rheum 44:819-25
Ezzo, J; Bausell, B; Moerman, D E et al. (2001) Reviewing the reviews. How strong is the evidence? How clear are the conclusions? Int J Technol Assess Health Care 17:457-66
Singh, B B; Berman, B M; Hadhazy, V et al. (2001) Clinical decisions in the use of acupuncture as an adjunctive therapy for osteoarthritis of the knee. Altern Ther Health Med 7:58-65
Berman, B M; Swyers, J P; Ezzo, J (2000) The evidence for acupuncture as a treatment for rheumatologic conditions. Rheum Dis Clin North Am 26:103-15, ix-x
Ezzo, J; Berman, B; Hadhazy, V A et al. (2000) Is acupuncture effective for the treatment of chronic pain? A systematic review. Pain 86:217-25
Berman, B M; Singh, B B; Lao, L et al. (1999) A randomized trial of acupuncture as an adjunctive therapy in osteoarthritis of the knee. Rheumatology (Oxford) 38:346-54
Berman, B M; Swyers, J P; Kaczmarczyk, J (1999) Complementary and alternative medicine: herbal therapies for diabetes. J Assoc Acad Minor Phys 10:10-4
Berman, B M; Ezzo, J; Hadhazy, V et al. (1999) Is acupuncture effective in the treatment of fibromyalgia? J Fam Pract 48:213-8