Studies are proposed to determine the properties of the ligaments, disks, and vertebral bodies of the human cervical spine in axial and eccentric compression, axial rotation and tension. Tension studies will be done on individual ligaments and disks in situ. All supporting tissue, except the element under study, will be eliminated at each spinal level. Similarly, the disks and vertebral bodies will be evaluated in compression and rotation. All the experiments will be done at 1 and 500 cm/s. Additionally, load relaxation studies and evaluations of intact cervical functional units will be conducted. Because the dimensions of the ligaments are difficult to determine in situ, selected cadavers will be sectioned using a cryomicrotome to visualize the cross-sectional anatomy. Photographs of the cross-sections will be digitized to determine the cross-sectional areas. The ultimate forces, deflection stresses and strains will be determined along with stiffness and elastic modulus for each element.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases (NIADDK)
Type
Unknown (R23)
Project #
1R23AM034271-01A1
Application #
3446030
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1985-09-20
Project End
1988-08-31
Budget Start
1985-09-20
Budget End
1986-08-31
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Type
Schools of Medicine
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Brown, C E; Srinivasan, R; Sigmann, P et al. (1988) Comparison of the compression strength of human vertebral bodies with the mass and density of apatite: a study by 31P NMR spectroscopy. Clin Chem 34:2114-7
Myklebust, J B; Pintar, F; Yoganandan, N et al. (1988) Tensile strength of spinal ligaments. Spine (Phila Pa 1976) 13:526-31
Yoganandan, N; Maiman, D J; Pintar, F et al. (1988) Microtrauma in the lumbar spine: a cause of low back pain. Neurosurgery 23:162-8
Yoganandan, N; Sances Jr, A; Maiman, D J et al. (1986) Experimental spinal injuries with vertical impact. Spine (Phila Pa 1976) 11:855-60