Current methods of predicting the amount of initial surgery needed to straighten the eyes of children with infantile (congenital) strabismus yield a success rate of no better than 70%. We hypothesize that the lack of success of the current method of prism cover measurement of the misalignment of the eyes is due in part to the method's failure to take into account the kinetic bias of the ocular motor system. This study will examine the relative contribution of a measure of the kinetic bias: the ability of a child with infantile strabismus to track an optokinetic stimulus moving in nasal and temporal direction under monocular viewing conditions. The ratio of optokinetic slow phase velocity to target velocity (gain) will be used as a predictor of surgical success.
| Tychsen, L; Lisberger, S G (1986) Maldevelopment of visual motion processing in humans who had strabismus with onset in infancy. J Neurosci 6:2495-508 |
| Tychsen, L; Lisberger, S G (1986) Visual motion processing for the initiation of smooth-pursuit eye movements in humans. J Neurophysiol 56:953-68 |
| Tychsen, L; Hurtig, R R; Scott, W E (1985) Pursuit is impaired but the vestibulo-ocular reflex is normal in infantile strabismus. Arch Ophthalmol 103:536-9 |
