Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Resource-Related Research Projects (R24)
Project #
5R24CA086307-04
Application #
6646620
Study Section
Special Emphasis Panel (ZRG1)
Project Start
2002-09-01
Project End
2003-08-31
Budget Start
Budget End
Support Year
4
Fiscal Year
2002
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Peng, Fangyu; Xie, Fang; Muzik, Otto (2018) Alteration of Copper Fluxes in Brain Aging: A Longitudinal Study in Rodent Using 64CuCl2-PET/CT. Aging Dis 9:109-118
Xie, Fang; Xi, Yin; Pascual, Juan M et al. (2017) Age-dependent changes of cerebral copper metabolism in Atp7b -/- knockout mouse model of Wilson's disease by [64Cu]CuCl2-PET/CT. Metab Brain Dis 32:717-726
Xie, Fang; Cai, Huawei; Peng, Fangyu (2017) 64CuCl2 PET/CT imaging of mouse muscular injury induced by electroporation. Am J Nucl Med Mol Imaging 7:33-39
Dearling, Jason L J; Paterson, Brett M; Akurathi, Vamsidhar et al. (2015) The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution. Bioconjug Chem 26:707-17
Peng, Fangyu; Muzik, Otto; Gatson, Joshua et al. (2015) Assessment of Traumatic Brain Injury by Increased 64Cu Uptake on 64CuCl2 PET/CT. J Nucl Med 56:1252-7
Cai, Huawei; Wu, Jiu-sheng; Muzik, Otto et al. (2014) Reduced 64Cu uptake and tumor growth inhibition by knockdown of human copper transporter 1 in xenograft mouse model of prostate cancer. J Nucl Med 55:622-8
O'Neill, Allison F; Dearling, Jason L J; Wang, Yuchuan et al. (2014) Targeted imaging of Ewing sarcoma in preclinical models using a 64Cu-labeled anti-CD99 antibody. Clin Cancer Res 20:678-87
Fu, Maoyong; Brewer, Sarah; Olafsen, Tove et al. (2013) Positron emission tomography imaging of endometrial cancer using engineered anti-EMP2 antibody fragments. Mol Imaging Biol 15:68-78
Yuan, Jianchao; Zhang, Haiyuan; Kaur, Harpreet et al. (2013) Synthesis and characterization of theranostic poly(HPMA)-c(RGDyK)-DOTA-64Cu copolymer targeting tumor angiogenesis: tumor localization visualized by positron emission tomography. Mol Imaging 12:203-12
Pressly, Eric D; Pierce, Richard A; Connal, Luke A et al. (2013) Nanoparticle PET/CT imaging of natriuretic peptide clearance receptor in prostate cancer. Bioconjug Chem 24:196-204

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