Microscopic Imaging: This module will provide equipment and technical assistance allowing members of the core to conduct quantitative analysis of cell and tissues using immunocytochemical, confocal microscopic morphometric and digital image processing approaches. The module will provide service contracts for the equipment, maintenance costs and dedicated research technical help to train interested investigators or directly perform specific research on the modules instruments. The module contains a Leica SP2 confocal microscope, an in vivo confocal microscope, Leica Diaplan epi-fluorescent microscope, equipment for quantitative microscopy and digital image processing, and equipment for microtomy and histology services.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Resource-Related Research Projects (R24)
Project #
5R24EY016664-05
Application #
7797379
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
5
Fiscal Year
2009
Total Cost
$122,011
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Ligocki, Ann J; Niederkorn, Jerry Y (2015) Advances on Non-CD4 + Foxp3+ T Regulatory Cells: CD8+, Type 1, and Double Negative T Regulatory Cells in Organ Transplantation. Transplantation 99:1553-9
Robertson, Danielle M; Kalangara, Jerry P; Baucom, Rebeccah B et al. (2011) A reconstituted telomerase-immortalized human corneal epithelium in vivo: a pilot study. Curr Eye Res 36:706-12
Ali, Zahra K; Whitson, Jess T; Mootha, V Vinod et al. (2011) Glaucoma in patients with corneal endothelial dystrophy. Eye Contact Lens 37:332-6
Coursey, Terry G; Chen, Peter W; Niederkorn, Jerry Y (2011) Abrogating TNF-? expression prevents bystander destruction of normal tissues during iNOS-mediated elimination of intraocular tumors. Cancer Res 71:2445-54
Arciniega, Juan Carlos; Wojtowicz, Jadwiga Cristina; Mohamed, Engy Mostafa et al. (2011) Changes in the evaporation rate of tear film after digital expression of meibomian glands in patients with and without dry eye. Cornea 30:843-7
Mootha, V Vinod; Heck, Ellen; Verity, Steven M et al. (2011) Comparative study of descemet stripping automated endothelial keratoplasty donor preparation by Moria CBm microkeratome, horizon microkeratome, and Intralase FS60. Cornea 30:320-4
Wojtowicz, Jadwiga Cristina; Butovich, Igor; Uchiyama, Eduardo et al. (2011) Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye. Cornea 30:308-14
Niederkorn, Jerry Y (2011) Cornea: Window to Ocular Immunology. Curr Immunol Rev 7:328-335
Lakshman, Neema; Kim, Areum; Petroll, W Matthew (2010) Characterization of corneal keratocyte morphology and mechanical activity within 3-D collagen matrices. Exp Eye Res 90:350-9
Kim, Areum; Lakshman, Neema; Karamichos, Dimitris et al. (2010) Growth factor regulation of corneal keratocyte differentiation and migration in compressed collagen matrices. Invest Ophthalmol Vis Sci 51:864-75

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