Substance use disorders (SUDs) are complex diseases with biopsychosocial underpinnings and multiple medical sequel that are best addressed by multidisciplinary teams of diverse individuals in the treatment and research realms. This proposal requests continued support of a grant (R25 DA020537) that was used to develop and implement several innovative programs, collectively known as the Drug Abuse Research Training (DART) programs, designed to increase the number of clinician-scientists committed to pursuing clinical research careers in the area of SUDs at the Medical University of South Carolina (MUSC). In the original project period, DART programs targeted psychiatry residents and medical students. In the renewal period, we propose to build on the success of the existing programs by expanding and diversifying the trainees involved in DART programs in strategic directions that align with the priorities of NIDA and the need for interdisciplinary team work that is mandated by the complexities of the patient population with SUDs.
The specific aims of the proposed research education training program are: 1) To continue to attract and train psychiatry residents committed to pursuing research careers focused on patient-oriented research in addictions; 2) To transform the DART Summer Research Fellowship for medical students into an interdisciplinary training program by including trainees from the Colleges of Nursing, Dental Medicine and Pharmacy; 3) To partner with the existing MUSC Summer Undergraduate Research Program (SURP) to offer a clinical research training experience focused on SUDs to select undergraduate students; 4) To partner with the training and training evaluation programs within the MUSC Clinical and Translational Science Institute (UL1 RR029882) so that DART trainees will benefit from CTSA educational resources and addiction research will gain increased visibility across the MUSC campus; 5) To conduct targeted outreach to under-represented minority trainees in all of the DART programs. The multidisciplinary training and partnerships with campus-wide training and research initiatives proposed will facilitate the collaborative clinical and research initiatives that will be necessary to meet critical workforce development needs and move the recognition and treatment of addictive disorders into the mainstream of medical practice.

Public Health Relevance

The participation of clinician-scientists in the biomedical research enterprise helps bridge the gap between basic science and clinical practice to address the healthcare needs of the public. In recent years the number of physicians engaged in research careers has declined by more than half, as have the number of research psychiatrists and research fellowships for psychiatrists. Interdisciplinary training focused on substance abuse disorders (SUDs) should facilitate the collaborative clinical and research initiatives that will be necessary to move the recognition and treatment of addictive disorders into mainstream medical practice.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Education Projects (R25)
Project #
5R25DA020537-10
Application #
8840555
Study Section
Special Emphasis Panel (ZDA1-GXM-A (01))
Program Officer
Aklin, Will
Project Start
2006-05-26
Project End
2016-04-30
Budget Start
2015-05-01
Budget End
2016-04-30
Support Year
10
Fiscal Year
2015
Total Cost
$281,594
Indirect Cost
$18,584
Name
Medical University of South Carolina
Department
Psychiatry
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29403
Williams, Nolan R; Bentzley, Brandon S; Hopkins, Thomas et al. (2018) Optimization of epidural cortical stimulation for treatment-resistant depression. Brain Stimul 11:239-240
Zuschlag, Zachary D; Korte, Jeffrey E; Hamner, Mark (2018) Predictors of Lifetime Suicide Attempts in Individuals With Attenuated Psychosis Syndrome. J Psychiatr Pract 24:169-178
Tolson, Celensia; Richey, Lauren E; Zhao, Yujing et al. (2018) Association of Substance Use With Hospitalization and Virologic Suppression in a Southern Academic HIV Clinic. Am J Med Sci 355:553-558
Back, Sudie E; Jones, Jennifer L (2018) Alcohol Use Disorder and Posttraumatic Stress Disorder: An Introduction. Alcohol Clin Exp Res 42:836-840
Jones, Jennifer L; Mateus, Camilo F; Malcolm, Robert J et al. (2018) Efficacy of Ketamine in the Treatment of Substance Use Disorders: A Systematic Review. Front Psychiatry 9:277
Tomko, Rachel L; Jones, Jennifer L; Gilmore, Amanda K et al. (2018) N-acetylcysteine: A potential treatment for substance use disorders. Curr Psychiatr 17:30-36, 41-42, 55
Cox, Brittney M; Bentzley, Brandon S; Regen-Tuero, Helaina et al. (2017) Oxytocin Acts in Nucleus Accumbens to Attenuate Methamphetamine Seeking and Demand. Biol Psychiatry 81:949-958
Flanagan, Julianne C; Fischer, Melanie S; Badour, Christal L et al. (2017) The Role of Relationship Adjustment in an Integrated Individual Treatment for PTSD and Substance Use Disorders Among Veterans: An Exploratory Study. J Dual Diagn 13:213-218
Campbell, Aimee N C; Back, Sudie E; Ostroff, Jamie S et al. (2017) Addiction Research Training Programs: Four Case Studies and Recommendations for Evaluation. J Addict Med 11:333-338
Szafranski, Derek D; Snead, Alexandra; Allan, Nicholas P et al. (2017) Integrated, exposure-based treatment for PTSD and comorbid substance use disorders: Predictors of treatment dropout. Addict Behav 73:30-35

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