The objective of the MBRS-IMSD Program at the University of California, Irvine (UCI) is to increase the number and academic excellence of underrepresented (UR) undergraduate and graduate students that complete PhD degrees in biomedical sciences and advance to competitive postdoctoral positions. During the past decade, program increased by severalfold the institutional rate at which UR undergraduates enter PhD programs following graduation and the number of UR graduate students completing PhD programs at UCI. Program elements are academic preparation, research training, intense mentoring and professional development. Independent paid research conducted under the direction of faculty mentors serves as a core element to prepare MBRS students for graduate school and research-focused careers. Research training begins in the freshmen year with the development of original projects that are developed by participants. Over 100 faculty with funded research programs serve as preceptors of MBRS trainees. The program offers a series of components to increase the interest, motivation and academic preparedness of undergraduates (freshmen to seniors) to enter PhD programs in biomedical sciences, including a peer tutoring/mentoring program of science classes, a seminar series, journal club, progress report sessions, workshops on scientific communications, and application to graduate school. The graduate component is designed to provide a comprehensive training for UR Ph.D. students to excel in graduate school. The program provides summer research training for incoming UR PhD students to prepare them for the graduate core classes, a workshop to prepare oral exams after the first year, a series of activities for second year students to prepare a dissertation research project and competitive proposals for extramural funding, presentation of papers at national conferences, professional development workshops on the academic postdoctoral positions search and counseling and orientation about graduate studies and career development in a non-departmental setting.

Public Health Relevance

The inclusion of underrepresented groups in the biomedical scientific workforce is critical to address the need of improving the health of the people of the United States and eliminating health disparities in the nation. This project will improve the quality and number of undergraduate and graduate students from underrepresented groups being trained as the next generation of biomedical research scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
5R25GM055246-18
Application #
8620662
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Janes, Daniel E
Project Start
1996-09-30
Project End
2017-12-31
Budget Start
2014-01-01
Budget End
2014-12-31
Support Year
18
Fiscal Year
2014
Total Cost
$637,909
Indirect Cost
$41,886
Name
University of California Irvine
Department
Type
Schools of Arts and Sciences
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697
Guerrero-Juarez, Christian F; Astrowski, Aliaksandr A; Murad, Rabi et al. (2018) Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis. J Invest Dermatol 138:1409-1419
Guerrero-Juarez, Christian F; Plikus, Maksim V (2018) Emerging nonmetabolic functions of skin fat. Nat Rev Endocrinol 14:163-173
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Zwick, Rachel K; Guerrero-Juarez, Christian F; Horsley, Valerie et al. (2018) Anatomical, Physiological, and Functional Diversity of Adipose Tissue. Cell Metab 27:68-83
Hughes, Michael W; Jiang, Ting-Xin; Plikus, Maksim V et al. (2018) Msx2 Supports Epidermal Competency during Wound-Induced Hair Follicle Neogenesis. J Invest Dermatol 138:2041-2050
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Lomeli, Naomi; Di, Kaijun; Czerniawski, Jennifer et al. (2017) Cisplatin-induced mitochondrial dysfunction is associated with impaired cognitive function in rats. Free Radic Biol Med 102:274-286
Plikus, Maksim V; Guerrero-Juarez, Christian F; Ito, Mayumi et al. (2017) Regeneration of fat cells from myofibroblasts during wound healing. Science 355:748-752
Catalan-Dibene, Jovani; Vazquez, Monica I; Luu, Van Phi et al. (2017) Identification of IL-40, a Novel B Cell-Associated Cytokine. J Immunol 199:3326-3335
Hernandez, Michael X; Jiang, Shan; Cole, Tracy A et al. (2017) Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. Mol Neurodegener 12:66

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