The revised SARETI III training program based at University of KwaZulu-Natal will build advanced African capacity for the ethical review and implementation of health research, and will continue to strengthen African capacity to sustain this aim. SARETI offers a comprehensive, multi-disciplinary, Africa-based Masters degree in health research ethics. The SARETI training program comprises a multi-disciplinary, modular Masters degree with funding for 19 trainees over the 5-year period of this award. More students will enroll for modules or degrees on a self- funded basis. The core of this intensive and advanced training program consists of: i) face-to-face modular coursework; ii) practical work with local ethics review committees (IRBs) and a leading NIH-funded African HIV/AIDS focused research centre (CAPRISA) funded by NIAID, FIC, and NIMH; iii) attendance of an intensive US-based bioethics program through the Johns Hopkins Bioethics Institute and the Kennedy Institute of Ethics;and iv) completion of an expanded research project on a topic relevant to health research ethics at the trainee's home institution or country, leading to submission to a peer-reviewed journal. After each year SARETI will support one top trainee to attend a unique four-week internship placement in Geneva at 1) COHRED/MARC, 2) the Ethics Review Committee of the World Health Organisation and 3) at the Faculty of Health Law at the University of Neuch?tel and TRREE, to consolidate their training and receive exposure to various top quality global research ethics related units and activities. In year five of the programme, SARETI will arrange its third Africa-wide Health Research Ethics Symposium (AHRES III) to allow trainees to share their scholarly work and ethics review experiences with their peers, to increase the African impact and networking of the SARETI training program, and to strengthen Africa's voice in this field. The 19 SARETI Masters (Research Ethics) graduates and SARETI faculty will contribute to the ethical conduct of appropriate health research and development in Africa by building IRB capacity, by training IRB members and researchers, and by promoting the global development and profile of African research ethics scholarship. The SARETI support programme ensures continuous development of Africa-based faculty. UKZN has expertise in Medicine, Psychology, Medical Sciences, Law, Human Rights, Philosophy, Ethics, Theology, Bioethics and Research Ethics, and has been providing high quality education in health research ethics since SARETI was launched in 2003. SARETI has strong links with African countries, the UK and the European Union to ensure a truly global applied perspective.

Public Health Relevance

The South African Research Ethics Training Initiative (SARETI) is the oldest and most established African-based Masters program in the field of health research ethics. The program equips African public health professionals with the education and practical experiences needed to provide sound ethics review of the increasingly numerous and complex health studies taking place in Africa. Since SARETI started in 2003 we have graduated 9 Masters (with 11 approaching completion), one PhD and 17 non-degree fellows, and are now applying for a third cycle of Fogarty funding to enroll a further 19 Masters students.

National Institute of Health (NIH)
Fogarty International Center (FIC)
Education Projects (R25)
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Special Emphasis Panel (ZRG1-HDM-B (50))
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Sina, Barbara J
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University of Kwazulu-Natal
South Africa
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Adewale, Babatunde; Schoeman, Lizette; Roussouw, Theresa (2015) Knowledge and perceptions of research participants in Nigeria about clinical trials. Indian J Med Ethics 12:196-8
Silaigwana, Blessing; Wassenaar, Douglas (2015) Biomedical Research Ethics Committees in sub-Saharan Africa: a collective review of their structure, functioning, and outcomes. J Empir Res Hum Res Ethics 10:169-84
Kombe, Francis; Anunobi, Eucharia Nkechinyere; Tshifugula, Nyanyukweni Pandeni et al. (2014) Promoting research integrity in Africa: an African voice of concern on research misconduct and the way forward. Dev World Bioeth 14:158-66
Okonta, Patrick I; Rossouw, Theresa (2014) Misconduct in research: a descriptive survey of attitudes, perceptions and associated factors in a developing country. BMC Med Ethics 15:25
Omondi Aduda, Dickens S; Mkhize, Nhlanhla (2014) Ethical issues evolving from patients' perspectives on compulsory screening for syphilis and voluntary screening for cervical cancer in Kenya. BMC Med Ethics 15:27
Ndebele, Paul; Wassenaar, Douglas; Masiye, Francis et al. (2014) Trial participants' understanding of randomization, double-blinding, and placebo use in low literacy populations: findings from a study conducted within a microbicide trial in Malawi. J Empir Res Hum Res Ethics 9:2-10
Okonta, Patrick; Rossouw, Theresa (2013) Prevalence of scientific misconduct among a group of researchers in Nigeria. Dev World Bioeth 13:149-57
Ndebele, Paul M; Wassenaar, Douglas; Munalula, Esther et al. (2012) Improving understanding of clinical trial procedures among low literacy populations: an intervention within a microbicide trial in Malawi. BMC Med Ethics 13:29
Wassenaar, Douglas R; Ramjee, Gita (2009) A developing country response to Lavery et al. ""In global health research, is it legitimate to stop clinical trials early on account of their opportunity costs?"". BMC Med Ethics 10:16