Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Unknown (R35)
Project #
5R35AG008974-06
Application #
5204660
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Sweet, Robert A; Panchalingam, Kanagasabai; Pettegrew, Jay W et al. (2002) Psychosis in Alzheimer disease: postmortem magnetic resonance spectroscopy evidence of excess neuronal and membrane phospholipid pathology. Neurobiol Aging 23:547-53
Pettegrew, J W; Panchalingam, K; Hamilton, R L et al. (2001) Brain membrane phospholipid alterations in Alzheimer's disease. Neurochem Res 26:771-82
Pettegrew, J W; Panchalingam, K; McClure, R J et al. (2001) Brain metabolic effects of acute nicotine. Neurochem Res 26:181-5
Fleck, M W; Barrionuevo, G; Palmer, A M (2001) Release of D,L-threo-beta-hydroxyaspartate as a false transmitter from excitatory amino acid-releasing nerve terminals. Neurochem Int 39:75-81
Fleck, M W; Barrionuevo, G; Palmer, A M (2001) Synaptosomal and vesicular accumulation of L-glutamate, L-aspartate and D-aspartate. Neurochem Int 39:217-25
Pettegrew, J W; Panchalingam, K; Levine, J et al. (2001) Chronic myo-inositol increases rat brain phosphatidylethanolamine plasmalogen. Biol Psychiatry 49:444-53
Pettegrew, J W; Klunk, W E; Panchalingam, K et al. (2000) Molecular insights into neurodevelopmental and neurodegenerative diseases. Brain Res Bull 53:455-69
Palmer, A M (2000) Preservation of N-methyl-D-aspartate receptor binding sites with age in rat neocortex. J Gerontol A Biol Sci Med Sci 55:B530-2
Palmer, A M (1999) The activity of the pentose phosphate pathway is increased in response to oxidative stress in Alzheimer's disease. J Neural Transm 106:317-28
Klunk, W E; Debnath, M L; Koros, A M et al. (1998) Chrysamine-G, a lipophilic analogue of Congo red, inhibits A beta-induced toxicity in PC12 cells. Life Sci 63:1807-14

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