Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Unknown (R35)
Project #
7R35AG010916-07
Application #
2690453
Study Section
Project Start
Project End
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
7
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Nathan Kline Institute for Psychiatric Research
Department
Type
DUNS #
167204762
City
Orangeburg
State
NY
Country
United States
Zip Code
10962
Nixon, Ralph A (2004) Niemann-Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up. Am J Pathol 164:757-61
Nixon, Ralph A (2003) The calpains in aging and aging-related diseases. Ageing Res Rev 2:407-18
Anderson, A J; Stoltzner, S; Lai, F et al. (2000) Morphological and biochemical assessment of DNA damage and apoptosis in Down syndrome and Alzheimer disease, and effect of postmortem tissue archival on TUNEL. Neurobiol Aging 21:511-24
Cataldo, A M; Peterhoff, C M; Troncoso, J C et al. (2000) Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations. Am J Pathol 157:277-86
Mathews, P M; Cataldo, A M; Kao, B H et al. (2000) Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease. Mol Med 6:878-91
Buchner, K; Adamec, E; Beermann, M L et al. (1999) Isoform-specific translocation of protein kinase C following glutamate administration in primary hippocampal neurons. Brain Res Mol Brain Res 64:222-35
Lai, F; Kammann, E; Rebeck, G W et al. (1999) APOE genotype and gender effects on Alzheimer disease in 100 adults with Down syndrome. Neurology 53:331-6
Adamec, E; Beermann, M L; Nixon, R A (1998) Calpain I activation in rat hippocampal neurons in culture is NMDA receptor selective and not essential for excitotoxic cell death. Brain Res Mol Brain Res 54:35-48
Troncoso, J C; Cataldo, A M; Nixon, R A et al. (1998) Neuropathology of preclinical and clinical late-onset Alzheimer's disease. Ann Neurol 43:673-6
Shea, T B; Dahl, D C; Nixon, R A et al. (1997) Triton-soluble phosphovariants of the heavy neurofilament subunit in developing and mature mouse central nervous system. J Neurosci Res 48:515-23

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