|
Mani, S; McDaid, H M; Grossman, A et al. (2007) Peripheral blood mononuclear and tumor cell pharmacodynamics of the novel epothilone B analogue, ixabepilone. Ann Oncol 18:190-5
|
|
Mani, Sridhar; Huang, Haiyan; Sundarababu, Sumathy et al. (2005) Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents. Clin Cancer Res 11:6359-69
|
|
Klein, Laura E; Freeze, B Scott; Smith 3rd, Amos B et al. (2005) The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence. Cell Cycle 4:501-7
|
|
Geney, Raphael; Sun, Liang; Pera, Paula et al. (2005) Use of the tubulin bound paclitaxel conformation for structure-based rational drug design. Chem Biol 12:339-48
|
|
Ikui, Amy E; Yang, Chia-Ping Huang; Matsumoto, Tomohiro et al. (2005) Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy. Cell Cycle 4:1385-8
|
|
Mani, Sridhar; McDaid, Hayley; Hamilton, Anne et al. (2004) Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors. Clin Cancer Res 10:1289-98
|
|
Chen, Jie-Guang; Yang, Chia-Ping Huang; Cammer, Michael et al. (2003) Gene expression and mitotic exit induced by microtubule-stabilizing drugs. Cancer Res 63:7891-9
|
|
Verdier-Pinard, Pascal; Wang, Fang; Burd, Berta et al. (2003) Direct analysis of tubulin expression in cancer cell lines by electrospray ionization mass spectrometry. Biochemistry 42:12019-27
|
|
Verdier-Pinard, Pascal; Wang, Fang; Martello, Laura et al. (2003) Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry. Biochemistry 42:5349-57
|
|
Martello, Laura A; Verdier-Pinard, Pascal; Shen, Heng-Jia et al. (2003) Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation. Cancer Res 63:1207-13
|
Showing the most recent 10 out of 76 publications
