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Smith, Robert A; Loeb, Lawrence A; Preston, Bradley D (2005) Lethal mutagenesis of HIV. Virus Res 107:215-28
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Shinkai, A; Patel, P H; Loeb, L A (2001) The conserved active site motif A of Escherichia coli DNA polymerase I is highly mutable. J Biol Chem 276:18836-42
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Skandalis, A; Loeb, L A (2001) Enzymatic properties of rat DNA polymerase beta mutants obtained by randomized mutagenesis. Nucleic Acids Res 29:2418-26
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Patel, P H; Kawate, H; Adman, E et al. (2001) A single highly mutable catalytic site amino acid is critical for DNA polymerase fidelity. J Biol Chem 276:5044-51
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Patel, P H; Loeb, L A (2000) Multiple amino acid substitutions allow DNA polymerases to synthesize RNA. J Biol Chem 275:40266-72
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Loeb, K R; Loeb, L A (2000) Significance of multiple mutations in cancer. Carcinogenesis 21:379-85
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Patel, P H; Loeb, L A (2000) DNA polymerase active site is highly mutable: evolutionary consequences. Proc Natl Acad Sci U S A 97:5095-100
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Silber, J R; Blank, A; Bobola, M S et al. (1999) O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy. Clin Cancer Res 5:807-14
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Loeb, L A; Essigmann, J M; Kazazi, F et al. (1999) Lethal mutagenesis of HIV with mutagenic nucleoside analogs. Proc Natl Acad Sci U S A 96:1492-7
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Encell, L P; Coates, M M; Loeb, L A (1998) Engineering human DNA alkyltransferases for gene therapy using random sequence mutagenesis. Cancer Res 58:1013-20
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