Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Unknown (R35)
Project #
5R35CA044339-10
Application #
2091423
Study Section
Special Emphasis Panel (SRC (88))
Project Start
1987-06-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Whitehead Institute for Biomedical Research
Department
Type
DUNS #
076580745
City
Cambridge
State
MA
Country
United States
Zip Code
02142
Hochedlinger, Konrad; Blelloch, Robert; Brennan, Cameron et al. (2004) Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev 18:1875-85
Humpherys, David; Eggan, Kevin; Akutsu, Hidenori et al. (2002) Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei. Proc Natl Acad Sci U S A 99:12889-94
Biniszkiewicz, Detlev; Gribnau, Joost; Ramsahoye, Bernard et al. (2002) Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Mol Cell Biol 22:2124-35
Eggan, Kevin; Rode, Anja; Jentsch, Isabell et al. (2002) Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nat Biotechnol 20:455-9
Akbarian, Schahram; Rios, Maribel; Liu, Rong-Jian et al. (2002) Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. J Neurosci 22:4153-62
Bates, Brian; Hirt, Lorenz; Thomas, Sunu S et al. (2002) Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals. Neurobiol Dis 9:24-37
Haase, V H; Glickman, J N; Socolovsky, M et al. (2001) Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. Proc Natl Acad Sci U S A 98:1583-8
Akbarian, S; Chen, R Z; Gribnau, J et al. (2001) Expression pattern of the Rett syndrome gene MeCP2 in primate prefrontal cortex. Neurobiol Dis 8:784-91
Csankovszki, G; Nagy, A; Jaenisch, R (2001) Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. J Cell Biol 153:773-84
Humpherys, D; Eggan, K; Akutsu, H et al. (2001) Epigenetic instability in ES cells and cloned mice. Science 293:95-7

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