Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Unknown (R35)
Project #
5R35CA049721-08
Application #
2093405
Study Section
Special Emphasis Panel (SRC (90))
Project Start
1989-05-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pathology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Johnson, Jennifer J; Chen, Weili; Hudson, Wendy et al. (2003) Prenatal and postnatal myeloid cells demonstrate stepwise progression in the pathogenesis of MLL fusion gene leukemia. Blood 101:3229-35
Li, Q; Hudson, W; Wang, D et al. (1998) Pharmacokinetics and biodistribution of radioimmunoconjugates of anti-CD19 antibody and single-chain Fv for treatment of human B-cell malignancy. Cancer Immunol Immunother 47:121-30
Hudson, W A; Li, Q; Le, C et al. (1998) Xenotransplantation of human lymphoid malignancies is optimized in mice with multiple immunologic defects. Leukemia 12:2029-33
Li, Q; Frestedt, J L; Kersey, J H (1998) AF4 encodes a ubiquitous protein that in both native and MLL-AF4 fusion types localizes to subnuclear compartments. Blood 92:3841-7
Kersey, J H; Wang, D; Oberto, M (1998) Resistance of t(4;11) (MLL-AF4 fusion gene) leukemias to stress-induced cell death: possible mechanism for extensive extramedullary accumulation of cells and poor prognosis. Leukemia 12:1561-4
Weisdorf, D J; Verfaille, C M; Miller, W J et al. (1997) Autologous bone marrow versus non-mobilized peripheral blood stem cell transplantation for lymphoid malignancies: a prospective, comparative trial. Am J Hematol 54:202-8
Wang, D; Berven, E; Li, Q et al. (1997) Optimization of conditions for formation and analysis of anti-CD19 FVS191 single-chain Fv homodimer (scFv')2. Bioconjug Chem 8:64-70
Lindstrom, A L; Erlandsen, S L; Kersey, J H et al. (1997) An in vitro model for toxin-mediated vascular leak syndrome: ricin toxin A chain increases the permeability of human endothelial cell monolayers. Blood 90:2323-34
Wang, D; Li, Q; Hudson, W et al. (1997) Generation and characterization of an anti-CD19 single-chain Fv immunotoxin composed of C-terminal disulfide-linked dgRTA. Bioconjug Chem 8:878-84
Hilden, J M; Frestedt, J L; Kersey, J H (1997) Molecular analysis of infant acute leukemia. Leuk Lymphoma 25:191-9

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