Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AG006108-08
Application #
3480133
Study Section
Special Emphasis Panel (NSS)
Project Start
1985-08-01
Project End
1992-07-31
Budget Start
1992-04-15
Budget End
1992-07-31
Support Year
8
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Medical College of Georgia (MCG)
Department
Type
Schools of Medicine
DUNS #
City
Augusta
State
GA
Country
United States
Zip Code
30912
Hornsby, P J; Thomas, M; Northrup, S R et al. (1998) Cell transplantation: a tool to study adrenocortical cell biology, physiology, and senescence. Endocr Res 24:909-18
Endoh, A; Yang, L; Hornsby, P J (1998) CYP21 pseudogene transcripts are much less abundant than those from the active gene in normal human adrenocortical cells under various conditions in culture. Mol Cell Endocrinol 137:13-9
Kristiansen, S B; Endoh, A; Casson, P R et al. (1997) Induction of steroidogenic enzyme genes by insulin and IGF-I in cultured adult human adrenocortical cells. Steroids 62:258-65
Didenko, V V; Hornsby, P J (1996) A quantitative luminescence assay for nonradioactive nucleic acid probes. J Histochem Cytochem 44:657-60
Didenko, V V; Wang, X; Yang, L et al. (1996) Expression of p21(WAF1/CIP1/SDI1) and p53 in apoptotic cells in the adrenal cortex and induction by ischemia/reperfusion injury. J Clin Invest 97:1723-31
Didenko, V V; Hornsby, P J (1996) Presence of double-strand breaks with single-base 3' overhangs in cells undergoing apoptosis but not necrosis. J Cell Biol 135:1369-76
Yang, L; Didenko, V V; Noda, A et al. (1995) Increased expression of p21Sdi1 in adrenocortical cells when they are placed in culture. Exp Cell Res 221:126-31
Maghsoudlou, S S; Hughes, T R; Hornsby, P J (1995) Analysis of the distal 5' region of the human CYP17 gene. Genome 38:845-9
Cheng, C Y; Hornsby, P J (1992) Expression of 11 beta-hydroxylase and 21-hydroxylase in long-term cultures of bovine adrenocortical cells requires extracellular matrix factors. Endocrinology 130:2883-9
Lala, D S; Hornsby, P J (1992) Activity of the CYP17 promoter in bovine adrenocortical cells before and after phenotypic switching. Mol Cell Endocrinol 89:19-24

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