Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37AG007444-08S2
Application #
2049753
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1988-03-01
Project End
1998-04-30
Budget Start
1995-09-30
Budget End
1996-04-30
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Mcgill University
Department
Type
DUNS #
City
Montreal
State
PQ
Country
Canada
Zip Code
H3 0-G4
Chang, Ruying; Wang, Eugenia (2007) Mouse translation elongation factor eEF1A-2 interacts with Prdx-I to protect cells against apoptotic death induced by oxidative stress. J Cell Biochem 100:267-78
Marcotte, Richard; Chen, Jen Mou; Huard, Sylvain et al. (2005) c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts. J Cell Biochem 96:1071-85
Marcotte, Richard; Lacelle, Chantale; Wang, Eugenia (2004) Senescent fibroblasts resist apoptosis by downregulating caspase-3. Mech Ageing Dev 125:777-83
Lacelle, Chantale; Riol, Helene; Xu, Suying et al. (2002) Blood-sample processing for the study of age-dependent gene expression in peripheral blood mononuclear cells. J Gerontol A Biol Sci Med Sci 57:B285-7
Lacelle, Chantale; Wang, Eugenia (2002) Establishing lymphoblastoid cell lines from frozen blood of extremely old individuals. Mech Ageing Dev 123:1415-8
Bernier, L; Wang, E (1996) A prospective view on phosphatases and replicative senescence. Exp Gerontol 31:13-9
Pandey, S; Gordon, P H; Wang, E (1995) Expression of proliferation-specific genes in the mucosa adjacent to colon carcinoma. Dis Colon Rectum 38:462-7
Wang, E; Lee, M J; Pandey, S (1994) Control of fibroblast senescence and activation of programmed cell death. J Cell Biochem 54:432-9
Sandig, M; Bissonnette, R; Liu, C H et al. (1994) Characterization of 57 kDa statin as a true marker for growth arrest in tissue by its disappearance from regenerating liver. J Cell Physiol 158:277-84
Lee, S; Wolfraim, L A; Wang, E (1993) Differential expression of S1 and elongation factor-1 alpha during rat development. J Biol Chem 268:24453-9

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