Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AG009383-24
Application #
8663760
Study Section
No Study Section (in-house review) (NSS)
Program Officer
Guo, Max
Project Start
1991-09-15
Project End
2017-03-31
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
24
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Alder, Jonathan K; Hanumanthu, Vidya Sagar; Strong, Margaret A et al. (2018) Diagnostic utility of telomere length testing in a hospital-based setting. Proc Natl Acad Sci U S A 115:E2358-E2365
Greider, Carol W (2016) Regulating telomere length from the inside out: the replication fork model. Genes Dev 30:1483-91
Lee, Stella Suyong; Bohrson, Craig; Pike, Alexandra Mims et al. (2015) ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells. Cell Rep 13:1623-32
Tom, Hui-I Kao; Greider, Carol W (2010) A sequence-dependent exonuclease activity from Tetrahymena thermophila. BMC Biochem 11:45
Chen, Jiunn-Liang; Greider, Carol W (2005) Functional analysis of the pseudoknot structure in human telomerase RNA. Proc Natl Acad Sci U S A 102:8080-5; discussion 8077-9
Chen, Jiunn-Liang; Greider, Carol W (2003) Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility. EMBO J 22:304-14
Chen, Jiunn-Liang; Greider, Carol W (2003) Template boundary definition in mammalian telomerase. Genes Dev 17:2747-52
Chen, Jiunn-Liang; Opperman, Kay Keyer; Greider, Carol W (2002) A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA. Nucleic Acids Res 30:592-7
Le, S; Sternglanz, R; Greider, C W (2000) Identification of two RNA-binding proteins associated with human telomerase RNA. Mol Biol Cell 11:999-1010
Le, S; Zhu, J J; Anthony, D C et al. (1998) Telomerase activity in human gliomas. Neurosurgery 42:1120-4;discussion 1124-5

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