Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AG012947-09
Application #
6631494
Study Section
Special Emphasis Panel (NSS)
Program Officer
Wise, Bradley C
Project Start
1995-05-25
Project End
2005-04-30
Budget Start
2003-05-15
Budget End
2004-04-30
Support Year
9
Fiscal Year
2003
Total Cost
$270,839
Indirect Cost

  Institution

Name
Washington University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Pierchala, Brian A; Tsui, Cynthia C; Milbrandt, Jeffrey et al. (2007) NGF augments the autophosphorylation of Ret via inhibition of ubiquitin-dependent degradation. J Neurochem 100:1169-76
Pierchala, Brian A; Milbrandt, Jeffrey; Johnson Jr, Eugene M (2006) Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation. J Neurosci 26:2777-87
Besirli, Cagri G; Johnson Jr, Eugene M (2006) The activation loop phosphorylation of protein kinase D is an early marker of neuronal DNA damage. J Neurochem 99:218-25
Leitner, Melanie L; Wang, Leo H; Osborne, Patricia A et al. (2005) Expression and function of GDNF family ligands and receptors in the carotid body. Exp Neurol 191 Suppl 1:S68-79
Besirli, Cagri G; Wagner, Erwin F; Johnson Jr, Eugene M (2005) The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway. J Cell Biol 170:401-11
Pierchala, Brian A; Ahrens, Rebecca C; Paden, Andrew J et al. (2004) Nerve growth factor promotes the survival of sympathetic neurons through the cooperative function of the protein kinase C and phosphatidylinositol 3-kinase pathways. J Biol Chem 279:27986-93
Putcha, G V; Johnson Jr, E M (2004) Men are but worms: neuronal cell death in C elegans and vertebrates. Cell Death Differ 11:38-48
Besirli, C G; Deckwerth, T L; Crowder, R J et al. (2003) Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons. Cell Death Differ 10:1045-58
Besirli, Cagri Giray; Johnson Jr, Eugene Malcolm (2003) JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents. J Biol Chem 278:22357-66
Putcha, Girish V; Le, Siyuan; Frank, Stephan et al. (2003) JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 38:899-914

Showing the most recent 10 out of 36 publications