Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI015122-31
Application #
6722818
Study Section
Special Emphasis Panel (NSS)
Program Officer
Park, Eun-Chung
Project Start
1978-04-01
Project End
2008-03-31
Budget Start
2004-04-01
Budget End
2005-03-31
Support Year
31
Fiscal Year
2004
Total Cost
$449,540
Indirect Cost
Name
State University New York Stony Brook
Department
Genetics
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Song, Yutong; Gorbatsevych, Oleksandr; Liu, Ying et al. (2017) Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes. Proc Natl Acad Sci U S A 114:E8731-E8740
Asare, Emmanuel; Mugavero, JoAnn; Jiang, Ping et al. (2016) A Single Amino Acid Substitution in Poliovirus Nonstructural Protein 2CATPase Causes Conditional Defects in Encapsidation and Uncoating. J Virol 90:6174-6186
Chen, Ying-Han; Du, WenLi; Hagemeijer, Marne C et al. (2015) Phosphatidylserine vesicles enable efficient en bloc transmission of enteroviruses. Cell 160:619-630
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Wang, Chunling; Ma, Hsin-Chieh; Wimmer, Eckard et al. (2014) A C-terminal, cysteine-rich site in poliovirus 2C(ATPase) is required for morphogenesis. J Gen Virol 95:1255-65
Ma, Hsin-Chieh; Liu, Ying; Wang, Chunling et al. (2014) An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses. PLoS Pathog 10:e1004052
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Wang, Chunling; Jiang, Ping; Sand, Claire et al. (2012) Alanine scanning of poliovirus 2CATPase reveals new genetic evidence that capsid protein/2CATPase interactions are essential for morphogenesis. J Virol 86:9964-75
Song, Yutong; Paul, Aniko V; Wimmer, Eckard (2012) Evolution of poliovirus defective interfering particles expressing Gaussia luciferase. J Virol 86:1999-2010
Toyoda, Hidemi; Wimmer, Eckard; Cello, Jeronimo (2011) Oncolytic poliovirus therapy and immunization with poliovirus-infected cell lysate induces potent antitumor immunity against neuroblastoma in vivo. Int J Oncol 38:81-7

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