Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI019149-11
Application #
2060875
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1986-09-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Toledo
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
807418939
City
Toledo
State
OH
Country
United States
Zip Code
43614
Herr, Roger A; Hung, Chiung-Yu; Cole, Garry T (2007) Evaluation of two homologous proline-rich proteins of Coccidioides posadasii as candidate vaccines against coccidioidomycosis. Infect Immun 75:5777-87
Hung, Chiung-Yu; Xue, Jianmin; Cole, Garry T (2007) Virulence mechanisms of coccidioides. Ann N Y Acad Sci 1111:225-35
Nosanchuk, Joshua D; Yu, Jieh-Juen; Hung, Chiung-Yu et al. (2007) Coccidioides posadasii produces melanin in vitro and during infection. Fungal Genet Biol 44:517-20
Fraser, James A; Stajich, Jason E; Tarcha, Eric J et al. (2007) Evolution of the mating type locus: insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii. Eukaryot Cell 6:622-9
Tarcha, Eric J; Basrur, Venkatesha; Hung, Chiung-Yu et al. (2006) A recombinant aspartyl protease of Coccidioides posadasii induces protection against pulmonary coccidioidomycosis in mice. Infect Immun 74:516-27
Tarcha, Eric J; Basrur, Venkatesha; Hung, Chiung-Yu et al. (2006) Multivalent recombinant protein vaccine against coccidioidomycosis. Infect Immun 74:5802-13
Kirkland, Theo N; Raz, Eyal; Datta, Sandip K (2006) Molecular and cellular mechanisms of protective immunity to coccidioidomycosis. Vaccine 24:495-500
Mirbod-Donovan, Fariba; Schaller, Ruth; Hung, Chiung-Yu et al. (2006) Urease produced by Coccidioides posadasii contributes to the virulence of this respiratory pathogen. Infect Immun 74:504-15
Yu, J-J; Kirkland, T N; Hall, L K et al. (2005) Characterization of a serodiagnostic complement fixation antigen of Coccidioides posadasii expressed in the nonpathogenic Fungus Uncinocarpus reesii. J Clin Microbiol 43:5462-9
Xue, Jianmin; Hung, Chiung-Yu; Yu, Jieh-Juen et al. (2005) Immune response of vaccinated and non-vaccinated mice to Coccidioides posadasii infection. Vaccine 23:3535-44

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