Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI019335-16
Application #
2060910
Study Section
Special Emphasis Panel (NSS)
Project Start
1990-06-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Bergsbaken, Tessa; Bevan, Michael J (2015) Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8? T cells responding to infection. Nat Immunol 16:406-14
Bergsbaken, Tessa; Bevan, Michael J (2015) Cutting Edge: Caspase-11 Limits the Response of CD8+ T Cells to Low-Abundance and Low-Affinity Antigens. J Immunol 195:41-5
Mehlhop-Williams, Erin R; Bevan, Michael J (2014) Memory CD8+ T cells exhibit increased antigen threshold requirements for recall proliferation. J Exp Med 211:345-56
Park, Heon; Tsang, Mark; Iritani, Brian M et al. (2014) Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development. Proc Natl Acad Sci U S A 111:7066-71
Chu, Talyn; Tyznik, Aaron J; Roepke, Sarah et al. (2013) Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner. Cell Rep 3:701-8
Zhang, Nu; Bevan, Michael J (2012) TGF-? signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation. Nat Immunol 13:667-73
Prlic, Martin; Sacks, Jilian A; Bevan, Michael J (2012) Dissociating markers of senescence and protective ability in memory T cells. PLoS One 7:e32576
Prlic, Martin; Bevan, Michael J (2011) Cutting edge: ?-catenin is dispensable for T cell effector differentiation, memory formation, and recall responses. J Immunol 187:1542-6
Pipkin, Matthew E; Sacks, Jilian A; Cruz-Guilloty, Fernando et al. (2010) Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 32:79-90
Zehn, Dietmar; Turner, Michael J; Lefrancois, Leo et al. (2010) Lack of original antigenic sin in recall CD8(+) T cell responses. J Immunol 184:6320-6

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