Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37AI020723-14S1
Application #
2720830
Study Section
Special Emphasis Panel (NSS)
Project Start
1984-06-01
Project End
2002-03-31
Budget Start
1997-04-01
Budget End
1998-03-31
Support Year
14
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Emory University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Bugrysheva, Julia V; Froehlich, Barbara J; Freiberg, Jeffrey A et al. (2011) The histone-like protein Hlp is essential for growth of Streptococcus pyogenes: comparison of genetic approaches to study essential genes. Appl Environ Microbiol 77:4422-8
Bugrysheva, Julia; Froehlich, Barbara J; Freiberg, Jeffrey A et al. (2011) Serine/threonine protein kinase Stk is required for virulence, stress response, and penicillin tolerance in Streptococcus pyogenes. Infect Immun 79:4201-9
Topp, Shana; Reynoso, Colleen M K; Seeliger, Jessica C et al. (2010) Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl Environ Microbiol 76:7881-4
Churchward, Gordon; Bates, Christopher; Gusa, Asiya A et al. (2009) Regulation of streptokinase expression by CovR/S in Streptococcus pyogenes: CovR acts through a single high-affinity binding site. Microbiology 155:566-75
Froehlich, Barbara J; Bates, Christopher; Scott, June R (2009) Streptococcus pyogenes CovRS mediates growth in iron starvation and in the presence of the human cationic antimicrobial peptide LL-37. J Bacteriol 191:673-7
Dalton, Tracy L; Scott, June R (2004) CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes. J Bacteriol 186:3928-37
Biswas, Indranil; Scott, June R (2003) Identification of rocA, a positive regulator of covR expression in the group A streptococcus. J Bacteriol 185:3081-90
Barnett, Timothy C; Scott, June R (2002) Differential recognition of surface proteins in Streptococcus pyogenes by two sortase gene homologs. J Bacteriol 184:2181-91
Federle, Michael J; Scott, June R (2002) Identification of binding sites for the group A streptococcal global regulator CovR. Mol Microbiol 43:1161-72
Limbago, B; McIver, K S; Penumalli, V et al. (2001) Restoration of Mga function to a Streptococcus pyogenes strain (M Type 50) that is virulent in mice. Infect Immun 69:1215-20

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