Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA016303-31
Application #
7010350
Study Section
Biochemical Endocrinology Study Section (BCE)
Program Officer
Yang, Shen K
Project Start
1978-08-01
Project End
2007-01-31
Budget Start
2006-02-01
Budget End
2007-01-31
Support Year
31
Fiscal Year
2006
Total Cost
$733,795
Indirect Cost
Name
Baylor College of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Sreekumar, Amulya; Toneff, Michael J; Toh, Eajer et al. (2017) WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis. Dev Cell 43:436-448.e6
Welte, Thomas; Zhang, Xiang H-F; Rosen, Jeffrey M (2017) Repurposing Antiestrogens for Tumor Immunotherapy. Cancer Discov 7:17-19
Zhang, Mei; Lee, Adrian V; Rosen, Jeffrey M (2017) The Cellular Origin and Evolution of Breast Cancer. Cold Spring Harb Perspect Med 7:
Shore, Amy N; Chang, Chi-Hsuan; Kwon, Oh-Joon et al. (2016) PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland. Dev Biol 409:202-217
Welte, Thomas; Kim, Ik Sun; Tian, Lin et al. (2016) Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol 18:632-44
Zhang, Mei; Rosen, Jeffrey M (2015) Developmental Insights into Breast Cancer Intratumoral Heterogeneity. Trends Cancer 1:242-251
Zhang, Mei; Tsimelzon, Anna; Chang, Chi-Hsuan et al. (2015) Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer. Cancer Discov 5:520-33
Sreekumar, Amulya; Roarty, Kevin; Rosen, Jeffrey M (2015) The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes. Endocr Relat Cancer 22:T161-76
Shore, Amy N; Rosen, Jeffrey M (2014) Regulation of mammary epithelial cell homeostasis by lncRNAs. Int J Biochem Cell Biol 54:318-30
Rosen, Jeffrey M; Roarty, Kevin (2014) Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity? Breast Cancer Res 16:202

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