Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37CA037157-09S1
Application #
3482372
Study Section
Experimental Virology Study Section (EVR)
Project Start
1992-06-01
Project End
1995-03-31
Budget Start
1992-06-01
Budget End
1993-03-31
Support Year
9
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Petti, Lisa M; Marlatt, Sara A; Luo, Yong et al. (2018) Regulation of C-C chemokine receptor 5 (CCR5) stability by Lys197 and by transmembrane protein aptamers that target it for lysosomal degradation. J Biol Chem 293:8787-8801
He, Li; Steinocher, Helena; Shelar, Ashish et al. (2017) Single methyl groups can act as toggle switches to specify transmembrane Protein-protein interactions. Elife 6:
Karabadzhak, Alexander G; Petti, Lisa M; Barrera, Francisco N et al. (2017) Two transmembrane dimers of the bovine papillomavirus E5 oncoprotein clamp the PDGF ? receptor in an active dimeric conformation. Proc Natl Acad Sci U S A 114:E7262-E7271
DiMaio, Daniel (2016) Thank You, Edward. Merci, Louis. PLoS Pathog 12:e1005320
Heim, Erin N; Marston, Jez L; Federman, Ross S et al. (2015) Biologically active LIL proteins built with minimal chemical diversity. Proc Natl Acad Sci U S A 112:E4717-25
Cohen, Emily B; Jun, Susan J; Bears, Zachary et al. (2014) Mapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor. PLoS One 9:e95593
Dimaio, Daniel (2014) Is virology dead? MBio 5:e01003-14
Chacón, Kelly M; Petti, Lisa M; Scheideman, Elizabeth H et al. (2014) De novo selection of oncogenes. Proc Natl Acad Sci U S A 111:E6-E14
Petti, Lisa M; Talbert-Slagle, Kristina; Hochstrasser, Megan L et al. (2013) A single amino acid substitution converts a transmembrane protein activator of the platelet-derived growth factor ? receptor into an inhibitor. J Biol Chem 288:27273-86
Edwards, Anne P B; Xie, Yanhua; Bowers, Lara et al. (2013) Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor ? receptor reveal a complex direct transmembrane interaction. J Virol 87:10936-45

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