Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA049816-08
Application #
2093470
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1989-06-01
Project End
1997-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Type
Schools of Pharmacy
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Tsai, Max; Lu, Ze; Wientjes, M Guillaume et al. (2013) Paclitaxel-loaded polymeric microparticles: quantitative relationships between in vitro drug release rate and in vivo pharmacodynamics. J Control Release 172:737-44
Hu, Leijun; Wientjes, M Guillaume; Li, Jing et al. (2010) Bladder tissue pharmacokinetics of intravesical mitomycin C and suramin in dogs. AAPS J 12:586-91
Lu, Ze; Wang, Jie; Wientjes, M Guillaume et al. (2010) Intraperitoneal therapy for peritoneal cancer. Future Oncol 6:1625-41
Lu, Ze; Tsai, Max; Lu, Dan et al. (2008) Tumor-penetrating microparticles for intraperitoneal therapy of ovarian cancer. J Pharmacol Exp Ther 327:673-82
Villalona-Calero, M A; Otterson, G A; Wientjes, M G et al. (2008) Noncytotoxic suramin as a chemosensitizer in patients with advanced non-small-cell lung cancer: a phase II study. Ann Oncol 19:1903-9
Tsai, Max; Lu, Ze; Wang, Jie et al. (2007) Effects of carrier on disposition and antitumor activity of intraperitoneal Paclitaxel. Pharm Res 24:1691-701
Chen, Danny; Song, Sae Heum; Wientjes, M Guillaume et al. (2006) Nontoxic suramin as a chemosensitizer in patients: dosing nomogram development. Pharm Res 23:1265-74
Wientjes, M Guillaume; Zheng, Jenny H; Hu, Leijun et al. (2005) Intraprostatic chemotherapy: distribution and transport mechanisms. Clin Cancer Res 11:4204-11
Xin, Yan; Lyness, Greg; Chen, Danny et al. (2005) Low dose suramin as a chemosensitizer of bladder cancer to mitomycin C. J Urol 174:322-7
Yeh, Teng Kuang; Lu, Ze; Wientjes, M Guillaume et al. (2005) Formulating paclitaxel in nanoparticles alters its disposition. Pharm Res 22:867-74

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