Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37CA050286-16
Application #
6682358
Study Section
Special Emphasis Panel (NSS)
Program Officer
Sathyamoorthy, Neeraja
Project Start
1989-08-01
Project End
2005-04-30
Budget Start
2004-05-01
Budget End
2005-04-30
Support Year
16
Fiscal Year
2004
Total Cost
$523,206
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
781613492
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Wang, Huawei; Lapek, John; Fujimura, Ken et al. (2018) Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription. Cell Discov 4:26
Desgrosellier, Jay S; Lesperance, Jacqueline; Seguin, Laetitia et al. (2014) Integrin ?v?3 drives slug activation and stemness in the pregnant and neoplastic mammary gland. Dev Cell 30:295-308
Seguin, Laetitia; Kato, Shumei; Franovic, Aleksandra et al. (2014) An integrin ??-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nat Cell Biol 16:457-68
Jean, Christine; Chen, Xiao Lei; Nam, Ju-Ock et al. (2014) Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function. J Cell Biol 204:247-63
Westenskow, Peter D; Kurihara, Toshihide; Aguilar, Edith et al. (2013) Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting. J Clin Invest 123:4900-8
Scheppke, Lea; Murphy, Eric A; Zarpellon, Alessandro et al. (2012) Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane. Blood 119:2149-58
Weis, Sara M; Cheresh, David A (2011) ?V integrins in angiogenesis and cancer. Cold Spring Harb Perspect Med 1:a006478
Weis, Sara M; Cheresh, David A (2011) Tumor angiogenesis: molecular pathways and therapeutic targets. Nat Med 17:1359-70
Mielgo, Ainhoa; Seguin, Laetitia; Huang, Miller et al. (2011) A MEK-independent role for CRAF in mitosis and tumor progression. Nat Med 17:1641-5
Anand, Sudarshan; Cheresh, David A (2011) MicroRNA-mediated regulation of the angiogenic switch. Curr Opin Hematol 18:171-6

Showing the most recent 10 out of 84 publications