Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
7R37CA050519-14
Application #
6948123
Study Section
Chemical Pathology Study Section (CPA)
Program Officer
Pelroy, Richard
Project Start
1989-07-01
Project End
2007-12-31
Budget Start
2004-10-01
Budget End
2004-12-31
Support Year
14
Fiscal Year
2004
Total Cost
$134,917
Indirect Cost

  Institution

Name
University of Texas Sw Medical Center Dallas
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390

  Publications

Mori, Eiichiro; Davis, Anthony J; Hasegawa, Masatoshi et al. (2016) Lysines 3241 and 3260 of DNA-PKcs are important for genomic stability and radioresistance. Biochem Biophys Res Commun 477:235-40
Davis, Anthony J; Lee, Kyung-Jong; Chen, David J (2013) The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation. J Biol Chem 288:7037-46
Wang, Hailong; Shi, Linda Z; Wong, Catherine C L et al. (2013) The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair. PLoS Genet 9:e1003277
Chung, Young Min; Park, See-Hyoung; Tsai, Wen-Bin et al. (2012) FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage. Nat Commun 3:1000
Sun, Jingxin; Lee, Kyung-Jong; Davis, Anthony J et al. (2012) Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presence of human Mre11 or Mre11/Rad50 protein complex. J Biol Chem 287:4936-45
Shao, Zhengping; Davis, Anthony J; Fattah, Kazi R et al. (2012) Persistently bound Ku at DNA ends attenuates DNA end resection and homologous recombination. DNA Repair (Amst) 11:310-6
Pankotai, Tibor; Bonhomme, Celine; Chen, David et al. (2012) DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks. Nat Struct Mol Biol 19:276-82
Segal-Raz, Hava; Mass, Gilad; Baranes-Bachar, Keren et al. (2011) ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair. EMBO Rep 12:713-9
Richard, Derek J; Savage, Kienan; Bolderson, Emma et al. (2011) hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex. Nucleic Acids Res 39:1692-702
Malewicz, Michal; Kadkhodaei, Banafsheh; Kee, Nigel et al. (2011) Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair. Genes Dev 25:2031-40

Showing the most recent 10 out of 103 publications