Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DE007907-10
Application #
2129915
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1988-12-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Dentistry
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Kho, H-S; Vacca Smith, A M; Koo, H et al. (2005) Interactions of Streptococcus mutans glucosyltransferase B with lysozyme in solution and on the surface of hydroxyapatite. Caries Res 39:411-6
Culp, D J; Quivey, R Q; Bowen, W H et al. (2005) A mouse caries model and evaluation of aqp5-/- knockout mice. Caries Res 39:448-54
Hayacibara, Mitsue F; Koo, Hyun; Vacca-Smith, Anne M et al. (2004) The influence of mutanase and dextranase on the production and structure of glucans synthesized by streptococcal glucosyltransferases. Carbohydr Res 339:2127-37
Koo, H; Hayacibara, M F; Schobel, B D et al. (2003) Inhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol. J Antimicrob Chemother 52:782-9
Korpela, A; Yu, X; Loimaranta, V et al. (2002) Lactoperoxidase inhibits glucosyltransferases from Streptococcus mutans in vitro. Caries Res 36:116-21
Kopec, Leslie K; Vacca Smith, Anne M; Wunder, David et al. (2002) Influence of antibody on the structure of glucans. Caries Res 36:108-15
Koo, H; Pearson, S K; Scott-Anne, K et al. (2002) Effects of apigenin and tt-farnesol on glucosyltransferase activity, biofilm viability and caries development in rats. Oral Microbiol Immunol 17:337-43
Kopec, L K; Vacca Smith, A M; Wunder, D et al. (2001) Properties of Streptococcus sanguinis glucans formed under various conditions. Caries Res 35:67-74
Wunder, D; Bowen, W H (2000) Effects of antibodies to glucosyltransferase on soluble and insolubilized enzymes. Oral Dis 6:289-96
Vacca Smith, A M; Bowen, W H (2000) The effects of milk and kappa-casein on salivary pellicle formed on hydroxyapatite discs in situ. Caries Res 34:88-93

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