Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37DK012121-27
Application #
2136709
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1977-01-01
Project End
1998-12-31
Budget Start
1994-01-01
Budget End
1994-12-31
Support Year
27
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
University of California Berkeley
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704

  Publications

Ames, G F; Nikaido, K; Wang, I X et al. (2001) Purification and characterization of the membrane-bound complex of an ABC transporter, the histidine permease. J Bioenerg Biomembr 33:79-92
Kreimer, D I; Chai, K P; Ferro-Luzzi Ames, G (2000) Nonequivalence of the nucleotide-binding subunits of an ABC transporter, the histidine permease, and conformational changes in the membrane complex. Biochemistry 39:14183-95
Liu, P Q; Liu, C E; Ames, G F (1999) Modulation of ATPase activity by physical disengagement of the ATP-binding domains of an ABC transporter, the histidine permease. J Biol Chem 274:18310-8
Nikaido, K; Ames, G F (1999) One intact ATP-binding subunit is sufficient to support ATP hydrolysis and translocation in an ABC transporter, the histidine permease. J Biol Chem 274:26727-35
Liu, C E; Liu, P Q; Wolf, A et al. (1999) Both lobes of the soluble receptor of the periplasmic histidine permease, an ABC transporter (traffic ATPase), interact with the membrane-bound complex. Effect of different ligands and consequences for the mechanism of action. J Biol Chem 274:739-47
Liu, P Q; Ames, G F (1998) In vitro disassembly and reassembly of an ABC transporter, the histidine permease. Proc Natl Acad Sci U S A 95:3495-500
Trakhanov, S; Kreimer, D I; Parkin, S et al. (1998) Cadmium-induced crystallization of proteins: II. Crystallization of the Salmonella typhimurium histidine-binding protein in complex with L-histidine, L-arginine, or L-lysine. Protein Sci 7:600-4
Liu, C E; Ames, G F (1997) Characterization of transport through the periplasmic histidine permease using proteoliposomes reconstituted by dialysis. J Biol Chem 272:859-66
Nikaido, K; Liu, P Q; Ames, G F (1997) Purification and characterization of HisP, the ATP-binding subunit of a traffic ATPase (ABC transporter), the histidine permease of Salmonella typhimurium. Solubility, dimerization, and ATPase activity. J Biol Chem 272:27745-52
Liu, C E; Liu, P Q; Ames, G F (1997) Characterization of the adenosine triphosphatase activity of the periplasmic histidine permease, a traffic ATPase (ABC transporter). J Biol Chem 272:21883-91

Showing the most recent 10 out of 48 publications