Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK015556-31
Application #
6380371
Study Section
Special Emphasis Panel (NSS)
Program Officer
Margolis, Ronald N
Project Start
1992-09-01
Project End
2003-08-31
Budget Start
2001-09-01
Budget End
2002-08-31
Support Year
31
Fiscal Year
2001
Total Cost
$282,426
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Srinivasan, Sathish; Nwachukwu, Jerome C; Bruno, Nelson E et al. (2017) Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nat Chem Biol 13:111-118
Zhao, Yuechao; Laws, Mary J; Guillen, Valeria Sanabria et al. (2017) Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors. Cancer Res 77:5602-5613
Martin, Anthony; Yu, Jiali; Xiong, Jian et al. (2017) Estrogens and androgens inhibit association of RANKL with the pre-osteoblast membrane through post-translational mechanisms. J Cell Physiol 232:3798-3807
Min, Jian; Guillen, Valeria Sanabria; Sharma, Abhishek et al. (2017) Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells. J Med Chem 60:6321-6336
Chambliss, Ken L; Barrera, Jose; Umetani, Michihisa et al. (2016) Nonnuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice. Endocrinology 157:3731-3741
Boonmuen, Nittaya; Gong, Ping; Ali, Zulfiqar et al. (2016) Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids 105:42-9
Nwachukwu, Jerome C; Srinivasan, Sathish; Zheng, Yangfan et al. (2016) Predictive features of ligand-specific signaling through the estrogen receptor. Mol Syst Biol 12:864
Madak-Erdogan, Zeynep; Kim, Sung Hoon; Gong, Ping et al. (2016) Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues. Sci Signal 9:ra53
Gong, Ping; Madak-Erdogan, Zeynep; Flaws, Jodi A et al. (2016) Estrogen receptor-? and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells. Mol Cell Endocrinol 437:190-200
Navarro, Guadalupe; Xu, Weiwei; Jacobson, David A et al. (2016) Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male. Cell Metab 23:837-51

Showing the most recent 10 out of 159 publications