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Huether, Robert; Liu, Zhi-Jie; Xu, Hao et al. (2010) Sequence fingerprint and structural analysis of the SCOR enzyme A3DFK9 from Clostridium thermocellum. Proteins 78:603-13
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Huether, Robert; Mao, Qilong; Duax, William L et al. (2010) The short-chain oxidoreductase Q9HYA2 from Pseudomonas aeruginosa PAO1 contains an atypical catalytic center. Protein Sci 19:1097-103
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Duax, William L; Huether, Robert; Pletnev, Vladimir et al. (2009) Divergent evolution of a Rossmann fold and identification of its oldest surviving ancestor. Int J Bioinform Res Appl 5:280-94
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Mao, Qilong; Duax, William L; Umland, Timothy C (2007) Crystallization and X-ray diffraction analysis of the beta-ketoacyl-acyl carrier protein reductase FabG from Aquifex aeolicus VF5. Acta Crystallogr Sect F Struct Biol Cryst Commun 63:106-9
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Sundlov, Jesse A; Garringer, Julie A; Carney, Jill M et al. (2006) Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli. Acta Crystallogr D Biol Crystallogr 62:734-40
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Duax, William L; Thomas, James; Pletnev, Vladimir et al. (2005) Determining structure and function of steroid dehydrogenase enzymes by sequence analysis, homology modeling, and rational mutational analysis. Ann N Y Acad Sci 1061:135-48
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Pletnev, Vladimir Z; Duax, William L (2005) Rational proteomics IV: modeling the primary function of the mammalian 17beta-hydroxysteroid dehydrogenase type 8. J Steroid Biochem Mol Biol 94:327-35
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Thomas, James L; Duax, William L; Addlagatta, Anthony et al. (2004) Structure/function aspects of human 3beta-hydroxysteroid dehydrogenase. Mol Cell Endocrinol 215:73-82
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Thomas, James L; Umland, Timothy C; Scaccia, Launa A et al. (2004) The higher affinity of human type 1 3beta-hydroxysteroid dehydrogenase (3beta-HSD1) for substrate and inhibitor steroids relative to human 3beta-HSD2 is validated in MCF-7 tumor cells and related to subunit interactions. Endocr Res 30:935-41
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Thomas, James L; Duax, William L; Addlagatta, Anthony et al. (2003) Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase. J Biol Chem 278:35483-90
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