Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DK036013-18
Application #
6928063
Study Section
Special Emphasis Panel (NSS)
Program Officer
Hamilton, Frank A
Project Start
1986-08-01
Project End
2009-08-31
Budget Start
2004-09-03
Budget End
2005-08-31
Support Year
18
Fiscal Year
2004
Total Cost
$309,800
Indirect Cost
Name
Tulane University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
053785812
City
New Orleans
State
LA
Country
United States
Zip Code
70118
Orlando, Roy C (2011) Dilated intercellular spaces and chronic cough as an extra-oesophageal manifestation of gastrooesophageal reflux disease. Pulm Pharmacol Ther 24:272-5
Jovov, Biljana; Que, Jianwen; Tobey, Nelia A et al. (2011) Role of E-cadherin in the pathogenesis of gastroesophageal reflux disease. Am J Gastroenterol 106:1039-47
Tobey, Nelia A; Djukic, Zorka; Brighton, Luisa E et al. (2010) Lateral cell membranes and shunt resistance in rabbit esophageal epithelium. Dig Dis Sci 55:1856-65
Orlando, Roy C (2010) The integrity of the esophageal mucosa. Balance between offensive and defensive mechanisms. Best Pract Res Clin Gastroenterol 24:873-82
Jovov, Biljana; Orlando, Geraldine S; Tobey, Nelia A et al. (2009) Ion transport and barrier function in a telomerase-immortalized human nondysplastic, Barrett's cell line (BAR-T). Dis Esophagus 22:386-95
Atug, Ozlen; Dobrucali, Ahmet; Orlando, Roy Charles (2009) Critical pH level of lye (NaOH) for esophageal injury. Dig Dis Sci 54:980-7
Tobey, N A; Gambling, T M; Vanegas, X C et al. (2008) Physicochemical basis for dilated intercellular spaces in non-erosive acid-damaged rabbit esophageal epithelium. Dis Esophagus 21:757-64
Orlando, Roy C (2008) Pathophysiology of gastroesophageal reflux disease. J Clin Gastroenterol 42:584-8
Abdulnour-Nakhoul, Solange; Tobey, Nelia A; Nakhoul, Nazih L et al. (2008) The effect of tegaserod on esophageal submucosal glands bicarbonate and mucin secretion. Dig Dis Sci 53:2366-72
Jovov, Biljana; Van Itallie, Christina M; Shaheen, Nicholas J et al. (2007) Claudin-18: a dominant tight junction protein in Barrett's esophagus and likely contributor to its acid resistance. Am J Physiol Gastrointest Liver Physiol 293:G1106-13

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