Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM009738-34
Application #
2168491
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
34
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Babitzke, P; Stults, J T; Shire, S J et al. (1994) TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis, is a multisubunit complex that appears to recognize G/UAG repeats in the trpEDCFBA and trpG transcripts. J Biol Chem 269:16597-604
Gish, K; Yanofsky, C (1993) Inhibition of expression of the tryptophanase operon in Escherichia coli by extrachromosomal copies of the tna leader region. J Bacteriol 175:3380-7
Babitzke, P; Yanofsky, C (1993) Reconstitution of Bacillus subtilis trp attenuation in vitro with TRAP, the trp RNA-binding attenuation protein. Proc Natl Acad Sci U S A 90:133-7
Kamath, A V; Yanofsky, C (1993) Sequence and characterization of mutT from Proteus vulgaris. Gene 134:99-102
Babitzke, P; Gollnick, P; Yanofsky, C (1992) The mtrAB operon of Bacillus subtilis encodes GTP cyclohydrolase I (MtrA), an enzyme involved in folic acid biosynthesis, and MtrB, a regulator of tryptophan biosynthesis. J Bacteriol 174:2059-64
Kamath, A V; Yanofsky, C (1992) Characterization of the tryptophanase operon of Proteus vulgaris. Cloning, nucleotide sequence, amino acid homology, and in vitro synthesis of the leader peptide and regulatory analysis. J Biol Chem 267:19978-85
Roesser, J R; Yanofsky, C (1991) The effects of leader peptide sequence and length on attenuation control of the trp operon of E.coli. Nucleic Acids Res 19:795-800
Landick, R; Yanofsky, C; Choo, K et al. (1990) Replacement of the Escherichia coli trp operon attenuation control codons alters operon expression. J Mol Biol 216:25-37
Roesser, J R; Yanofsky, C (1990) The RNA antiterminator causes transcription pausing in the leader region of the tryptophan operon. J Biol Chem 265:6055-60
Gollnick, P; Ishino, S; Kuroda, M I et al. (1990) The mtr locus is a two-gene operon required for transcription attenuation in the trp operon of Bacillus subtilis. Proc Natl Acad Sci U S A 87:8726-30

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