Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
7R37GM026782-28
Application #
6913648
Study Section
Special Emphasis Panel (NSS)
Program Officer
Schwab, John M
Project Start
1987-02-01
Project End
2008-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
28
Fiscal Year
2005
Total Cost
$264,200
Indirect Cost
Name
Scripps Florida
Department
Type
DUNS #
148230662
City
Jupiter
State
FL
Country
United States
Zip Code
33458
Doherty, Joanne R; Yang, Chunying; Scott, Kristen E N et al. (2014) Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis. Cancer Res 74:908-20
Dossey, Aaron T; Whitaker, John M; Dancel, Maria Cristina A et al. (2012) Defensive spiroketals from Asceles glaber (Phasmatodea): absolute configuration and effects on ants and mosquitoes. J Chem Ecol 38:1105-15
Chen, Ming; Roush, William R (2011) Enantioconvergent hydroboration of a racemic allene: enantioselective synthesis of (E)-ýý-stannyl-anti-homoallylic alcohols via aldehyde crotylboration. J Am Chem Soc 133:5744-7
Stewart, Preston S; Chen, Ming; Roush, William R et al. (2011) Thermodynamic control of 1,3-boratropic shifts of ?- and ?-stannyl-substituted allylboranes: hyperconjugation outweighs steric effects. Org Lett 13:1478-81
Halvorsen, Geoff T; Roush, William R (2011) Stereoselective Synthesis of the Decahydrofluorene Core of the Hirsutellones. Tetrahedron Lett 52:2072-2075
Sun, Huikai; Abbott, Jason R; Roush, William R (2011) Stereoselective synthesis of a model C(18)-C(35) spiroketal fragment of integramycin. Org Lett 13:2734-7
Chen, Ming; Ess, Daniel H; Roush, William R (2010) Enantioselective synthesis of (E)-delta-stannyl homoallylic alcohols via aldehyde allylboration using alpha-stannylallylboranes generated by allene hydroboration followed by a highly diastereoselective 1,3-boratropic shift. J Am Chem Soc 132:7881-3
Chen, Ming; Roush, William R (2010) Highly (E)-selective BF(3).Et(2)O-promoted allylboration of chiral nonracemic alpha-substituted allylboronates and analysis of the origin of stereocontrol. Org Lett 12:2706-9
Chen, Ming; Handa, Masaki; Roush, William R (2009) Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences. J Am Chem Soc 131:14602-3
Ess, Daniel H; Kister, Jeremy; Chen, Ming et al. (2009) Quantum-mechanical study of 10-R-9-borabicyclo[3.3.2]decane alkene hydroboration. J Org Chem 74:8626-37

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