Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37GM036806-19S1
Application #
6946282
Study Section
Special Emphasis Panel (NSS)
Program Officer
Rodewald, Richard D
Project Start
1986-07-01
Project End
2009-07-31
Budget Start
2004-08-01
Budget End
2005-07-31
Support Year
19
Fiscal Year
2004
Total Cost
$111,375
Indirect Cost
Name
Northwestern University at Chicago
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Helfand, Brian T; Mendez, Melissa G; Murthy, S N Prasanna et al. (2011) Vimentin organization modulates the formation of lamellipodia. Mol Biol Cell 22:1274-89
Ralat, Luis A; Kalas, Vasilios; Zheng, Zhongzhou et al. (2011) Ubiquitin is a novel substrate for human insulin-degrading enzyme. J Mol Biol 406:454-66
Nekrasova, Oxana E; Mendez, Melissa G; Chernoivanenko, Ivan S et al. (2011) Vimentin intermediate filaments modulate the motility of mitochondria. Mol Biol Cell 22:2282-9
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Flitney, Eric W; Kuczmarski, Edward R; Adam, Stephen A et al. (2009) Insights into the mechanical properties of epithelial cells: the effects of shear stress on the assembly and remodeling of keratin intermediate filaments. FASEB J 23:2110-9
Jaitovich, Ariel; Mehta, Semil; Na, Ni et al. (2008) Ubiquitin-proteasome-mediated degradation of keratin intermediate filaments in mechanically stimulated A549 cells. J Biol Chem 283:25348-55
Sivaramakrishnan, Sivaraj; DeGiulio, James V; Lorand, Laszlo et al. (2008) Micromechanical properties of keratin intermediate filament networks. Proc Natl Acad Sci U S A 105:889-94
Goldman, Robert D; Grin, Boris; Mendez, Melissa G et al. (2008) Intermediate filaments: versatile building blocks of cell structure. Curr Opin Cell Biol 20:28-34
Chang, Lynne; Shav-Tal, Yaron; Trcek, Tatjana et al. (2006) Assembling an intermediate filament network by dynamic cotranslation. J Cell Biol 172:747-58
Helfand, Brian T; Chou, Ying-Hao; Shumaker, Dale K et al. (2005) Intermediate filament proteins participate in signal transduction. Trends Cell Biol 15:568-70

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