Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL013531-24
Application #
2214753
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
24
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201
Davydov, Roman; Im, Sangchoul; Shanmugam, Muralidharan et al. (2016) Role of the Proximal Cysteine Hydrogen Bonding Interaction in Cytochrome P450 2B4 Studied by Cryoreduction, Electron Paramagnetic Resonance, and Electron-Nuclear Double Resonance Spectroscopy. Biochemistry 55:869-83
Davydov, Roman; Labby, Kristin Jansen; Chobot, Sarah E et al. (2014) Enzymatic and cryoreduction EPR studies of the hydroxylation of methylated N(?)-hydroxy-L-arginine analogues by nitric oxide synthase from Geobacillus stearothermophilus. Biochemistry 53:6511-9
Ortony, Julia H; Newcomb, Christina J; Matson, John B et al. (2014) Internal dynamics of a supramolecular nanofibre. Nat Mater 13:812-6
Hoffman, Brian M; Lukoyanov, Dmitriy; Yang, Zhi-Yong et al. (2014) Mechanism of nitrogen fixation by nitrogenase: the next stage. Chem Rev 114:4041-62
Lukoyanov, Dmitriy; Yang, Zhi-Yong; Duval, Simon et al. (2014) A confirmation of the quench-cryoannealing relaxation protocol for identifying reduction states of freeze-trapped nitrogenase intermediates. Inorg Chem 53:3688-93
Hoffman, Brian M; Lukoyanov, Dmitriy; Dean, Dennis R et al. (2013) Nitrogenase: a draft mechanism. Acc Chem Res 46:587-95
Sharma, Ajay; Gaidamakova, Elena K; Matrosova, Vera Y et al. (2013) Responses of Mn2+ speciation in Deinococcus radiodurans and Escherichia coli to ?-radiation by advanced paramagnetic resonance methods. Proc Natl Acad Sci U S A 110:5945-50
Davydov, Roman; Dawson, John H; Perera, Roshan et al. (2013) The use of deuterated camphor as a substrate in (1)H ENDOR studies of hydroxylation by cryoreduced oxy P450cam provides new evidence of the involvement of compound I. Biochemistry 52:667-71
Yang, Zhi-Yong; Khadka, Nimesh; Lukoyanov, Dmitriy et al. (2013) On reversible H2 loss upon N2 binding to FeMo-cofactor of nitrogenase. Proc Natl Acad Sci U S A 110:16327-32
Davydov, Roman M; McLaughlin, Matthew P; Bill, Eckhard et al. (2013) Generation of high-spin iron(I) in a protein environment using cryoreduction. Inorg Chem 52:7323-5

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