Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
7R37HL033756-10
Application #
3486067
Study Section
Special Emphasis Panel (NSS)
Project Start
1987-04-01
Project End
1997-03-31
Budget Start
1992-12-01
Budget End
1993-03-31
Support Year
10
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Ghatak, Shibnath; Vyas, Alok; Misra, Suniti et al. (2014) Novel di-tertiary-butyl phenylhydrazones as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, COX/LOX inhibition, molecular modeling, and insights into their cytotoxicities. Bioorg Med Chem Lett 24:317-24
Inai, Kei; Burnside, Jessica L; Hoffman, Stanley et al. (2013) BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration. PLoS One 8:e77593
Kolpa, Heather J; Peal, David S; Lynch, Stacey N et al. (2013) miR-21 represses Pdcd4 during cardiac valvulogenesis. Development 140:2172-80
Misra, Suniti; Ghatak, Shibnath; Patil, Neha et al. (2013) Novel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan-CD44v6 pathway and inducing cytotoxicity in colon cancer cells. Bioorg Med Chem 21:2551-9
Yalcin, Huseyin C; Shekhar, Akshay; McQuinn, Tim C et al. (2011) Hemodynamic patterning of the avian atrioventricular valve. Dev Dyn 240:23-35
Markwald, Roger R; Norris, Russell A; Moreno-Rodriguez, Ricardo et al. (2010) Developmental basis of adult cardiovascular diseases: valvular heart diseases. Ann N Y Acad Sci 1188:177-83
Chiu, Yung-Nung; Norris, Russell A; Mahler, Gretchen et al. (2010) Transforming growth factor *, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering. Tissue Eng Part A 16:3375-83
Norris, R A; Moreno-Rodriguez, R; Wessels, A et al. (2010) Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis. Dev Dyn 239:2118-27
Teekakirikul, Polakit; Eminaga, Seda; Toka, Okan et al. (2010) Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-ýý. J Clin Invest 120:3520-9
Tkatchenko, Tatiana V; Moreno-Rodriguez, Ricardo A; Conway, Simon J et al. (2009) Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Physiol Genomics 39:160-8

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