Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL036473-11
Application #
2218171
Study Section
Special Emphasis Panel (NSS)
Project Start
1988-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Pharmacology
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Zhang, Xianming; Lowry, Jessica L; Brovkovych, Viktor et al. (2012) Characterization of dual agonists for kinin B1 and B2 receptors and their biased activation of B2 receptors. Cell Signal 24:1619-31
Brovkovych, Viktor; Zhang, Yongkang; Brovkovych, Svitlana et al. (2011) A novel pathway for receptor-mediated post-translational activation of inducible nitric oxide synthase. J Cell Mol Med 15:258-69
Erdös, Ervin G; Tan, Fulong; Skidgel, Randal A (2010) Angiotensin I-converting enzyme inhibitors are allosteric enhancers of kinin B1 and B2 receptor function. Hypertension 55:214-20
Keil, Cora; Maskos, Klaus; Than, Manuel et al. (2007) Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain. J Mol Biol 366:504-16
Skidgel, Randal A; Stanisavljevic, Sinisa; Erdos, Ervin G (2006) Kinin- and angiotensin-converting enzyme (ACE) inhibitor-mediated nitric oxide production in endothelial cells. Biol Chem 387:159-65
Quagraine, Mercy O; Tan, Fulong; Tamei, Hironori et al. (2005) Plasmin alters the activity and quaternary structure of human plasma carboxypeptidase N. Biochem J 388:81-91
Ignjatovic, Tatjana; Stanisavljevic, Sinisa; Brovkovych, Viktor et al. (2004) Kinin B1 receptors stimulate nitric oxide production in endothelial cells: signaling pathways activated by angiotensin I-converting enzyme inhibitors and peptide ligands. Mol Pharmacol 66:1310-6
Deddish, Peter A; Marcic, Branislav M; Tan, Fulong et al. (2002) Neprilysin inhibitors potentiate effects of bradykinin on b2 receptor. Hypertension 39:619-23
Ignjatovic, Tatjana; Tan, Fulong; Brovkovych, Viktor et al. (2002) Activation of bradykinin B1 receptor by ACE inhibitors. Int Immunopharmacol 2:1787-93
Ignjatovic, Tatjana; Tan, Fulong; Brovkovych, Viktor et al. (2002) Novel mode of action of angiotensin I converting enzyme inhibitors: direct activation of bradykinin B1 receptor. J Biol Chem 277:16847-52

Showing the most recent 10 out of 68 publications