Otoreflectance (OR) is a new class of hearing test instruments utilizing acoustic signals presented and recorded in the ear canal. OR instruments address limitations in existing screening and diagnostic instruments in such areas as: (1) detecting otitis media, (2) predicting conductive hearing loss, (3) augmenting the newborn hearing screening protocol to test for middle-ear dysfunction, and (4) the general assessment of middle-ear functioning at frequencies important for speech perception. OR provides calibrated measurements over a frequency range from approximately 0.25 to 8 kHz of such transfer functions as reflectance and admittance, and the power absorbed by the ear canal and middle ear. Energy reflectance and absorbed power are OR functions that are relatively insensitive to the position of the probe in the ear canal. This property may allow clinical interpretation of these functions at moderate and high frequencies at which the tympanometric admittance, which is sensitive to probe position, becomes difficult to interpret. One proposed class of OR instruments can be used with probes similar to otoacoustic emission probes to screen middle-ear functioning in several seconds at ambient pressure in the ear canal. Such rapidly performed measurements at ambient pressure may provide a test of middle-ear dysfunction in newborn hearing screening programs, and a test to screen for conductive hearing loss in children at risk for otitis media with effusion. Another proposed class of OR instruments, for which a static pressure pump will be added to the probe system, will be used to measured reflectance, admittance and absorbed power as functions of both frequency and static pressure in the ear canal. Such OR tympanometry instruments may have general audiological and screening utility for diagnosing middle-ear pathology due to the fact that the energy reflectance tympanogram has more orderly patterns at moderate and high frequencies than multifrequency tympanometers based only on admittance. A third proposed class of OR instruments may provide a sensitive test of the acoustic reflex threshold by measuring the wideband shift in OR responses elicited by a contralateral or ipsilateral activator sound. A protocol to measure supra-threshold reflex decay may provide additional wideband information that is unavailable in clinical reflex testing.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Small Business Technology Transfer (STTR) Grants - Phase I (R41)
Project #
1R41DC006607-01
Application #
6744273
Study Section
Special Emphasis Panel (ZRG1-IFCN-6 (10))
Program Officer
Luethke, Lynn E
Project Start
2003-09-26
Project End
2005-02-28
Budget Start
2003-09-26
Budget End
2005-02-28
Support Year
1
Fiscal Year
2003
Total Cost
$99,840
Indirect Cost
Name
Sonicom, Inc.
Department
Type
DUNS #
090584819
City
Omaha
State
NE
Country
United States
Zip Code
68124
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Keefe, Douglas H; Sanford, Chris A; Ellison, John C et al. (2012) Wideband aural acoustic absorbance predicts conductive hearing loss in children. Int J Audiol 51:880-91
Keefe, Douglas H; Schairer, Kim S (2011) Specification of absorbed-sound power in the ear canal: application to suppression of stimulus frequency otoacoustic emissions. J Acoust Soc Am 129:779-91
Keefe, Douglas H; Fitzpatrick, Denis; Liu, Yi-Wen et al. (2010) Wideband acoustic-reflex test in a test battery to predict middle-ear dysfunction. Hear Res 263:52-65
Sanford, Chris A; Keefe, Douglas H; Liu, Yi-Wen et al. (2009) Sound-conduction effects on distortion-product otoacoustic emission screening outcomes in newborn infants: test performance of wideband acoustic transfer functions and 1-kHz tympanometry. Ear Hear 30:635-52