The human microbiome has emerged as a hitherto unknown causal factor in a number of disease, ranging from cancer, cardiovascular disease, and obesity. To understand the biochemical mechanisms of the human microbiome in these diseases, researchers must be able to store biochemical pathway, transcriptomic, and metabolomic datasets in a coherent and compatible form. We propose to construct a cloud-based microbiome analytics platform service that provides both common data processing tools, along with integration of a standards-compliant database that can be queried to provide cross-dataset and inter-modal data comparative analytics.

Public Health Relevance

The human microbiome is the collection of bacteria that live inside of all people, and researchers have determined that these bacteria play a causal role in many diseases such as obesity. Our proposal will create an analysis system for processing large volumes of data from the human microbiome, allowing efficient and easy data processing for both academic researchers and for-profit biotechnology companies.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Small Business Technology Transfer (STTR) Grants - Phase I (R41)
Project #
1R41GM121144-01
Application #
9202897
Study Section
Special Emphasis Panel (ZRG1-IMST-K (14)B)
Program Officer
Ravichandran, Veerasamy
Project Start
2016-09-09
Project End
2017-03-08
Budget Start
2016-09-09
Budget End
2017-03-08
Support Year
1
Fiscal Year
2016
Total Cost
$224,997
Indirect Cost
Name
Whole Biome, Inc.
Department
Type
DUNS #
050156190
City
San Francisco
State
CA
Country
United States
Zip Code
94107