Insect-borne disease is a world-wide problem of enormous scale and devastating impact, particularly in less developed countries. Despite the development of new insecticides, current techniques of using a single insecticide over long periods of time for mosquito control result in acquired resistance posing a significant risk of loss of effectiveness of insecticides. This proposal describes a novel approach to the formation of insecticidal bednets. Instead of using a chemical insecticide, bed nets are modified to have unique physical properties to deter insect contact with the clothing, thereby minimizing the risk of bites or stings. The protective surface finish does not present any health hazard, no harmful chemicals are released into the environment, and the finish can potentially be universally applied to multiple fabric types with only minimal changes to the fabric?s physical properties including breathability/comfort. This Proof-of-concept study will develop an industrially viable and scalable process for production of bed net fabric materials with non-chemical insect protection. It is expected that, once the science has been established for bed net clothing, the proposed non- chemical insect-repellant textiles will have multiple applications including outdoor sportswear, wall coverings, window curtains and outdoor upholstery items. Non-chemical methods are less vulnerable to biological resistance, and could help reduce disease prevalence. In the developed world, the sports and recreation market is a substantial commercial opportunity.

Public Health Relevance

This proposal describes development of next generation of insecticidal textiles that will rely solely on non-chemical, non-toxic, and risk-free insecticidal properties for use in clothing and bedding. These textiles will be impenetrable by the insect and will protect the individual from bites. Additionally, the textiles will protect the broader community by disabling the mosquitoes? ability to transmit disease by killing it on contact.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43AI126957-01
Application #
9200399
Study Section
Special Emphasis Panel (ZRG1-IDM-X (10)B)
Program Officer
Costero-Saint Denis, Adriana
Project Start
2016-08-01
Project End
2017-07-31
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
1
Fiscal Year
2016
Total Cost
$231,117
Indirect Cost
Name
Lynntech, Inc.
Department
Type
DUNS #
184758308
City
College Station
State
TX
Country
United States
Zip Code
77845