The objective of this research project is to demonstrate the feasibility of utilizing a newly developed family of microporous membranes for burn dressing applications. A silicone based interpenetrating polymer network (""""""""IPN"""""""") has been developed, and the microporous membrane is capable of being coated on one side with a crosslinked network of collagen and glycosaminoglycan. The moisture vapor transmission rate of the transparent IPN can be precisely controlled; furthermore, the material is an effective bacteria barrier and has excellent hand or drapability characteristics. This project will specifically explore the feasibility of using such membranes as a supportive matrix for the biodegradable protein layer of a transparent burn dressing. Long term objectives: Provide new burn dressing material Evaluate other medical applications Methodology: Produce membrane samples Evaluate production methodology In vitro characterization Prototype production Technological Innovation: Newly developed biocompatible IPN Composite style properties Controllable MVTR

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43AR040483-01
Application #
3490570
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1990-09-20
Project End
1991-03-19
Budget Start
1990-09-20
Budget End
1991-03-19
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Bio Med Sciences, Inc.
Department
Type
DUNS #
City
Bethlehem
State
PA
Country
United States
Zip Code
18015