Development of a Tm:YLF solid-state laser surgical system is proposed which will utilize a new type of efficient, laser-diode-pumping scheme. This scheme is easily scalable to high-average-power operation. The laser is expected to produce tissue interaction effects like those of the 10-micrometer-wavelength C02 laser, but with the advantage that its 1.95-micrometer-wavelength is easily transmitted by standard, flexible, low-OH silica fibers. Interacting with malignant or viral lesions, the CW-mode of operation is expected to produce lower emission of viable biological material than the pulsed-mode laser operation, typical of flash-lamp-pumped, solid-state lasers operating in the 2 micrometer output-wavelength range. The new laser-diode-pumped-laser technique, to be utilized in this project, is also easily adaptable to pulsed-laser-diode-pumping and thus will allow construction of compact and efficient, CW or pulsed, medical laser systems operating near the 1.93 micrometer water absorption peak. Such systems will find ready applications in many excision/coagulation/cutting procedures where the need for flexible fiber delivery or the need to work in a liquid filled field prevents easy application of a C02 laser.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43CA054670-01
Application #
3492835
Study Section
Special Emphasis Panel (SSS (B1))
Project Start
1991-05-03
Project End
1992-03-31
Budget Start
1991-05-03
Budget End
1992-03-31
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Quantronix Corporation
Department
Type
DUNS #
City
Hauppauge
State
NY
Country
United States
Zip Code
11788
Goodwin, J S; Nattinger, A B (1995) Effect of season and climate on choice of therapy for breast cancer in older women. J Am Geriatr Soc 43:962-6