Many anti-cancer drugs are high insoluble in aqueous media and difficult to recover from microbial and plant cells where they are produced. This proposal sets forth an investigation of the application of a novel separation/purification approach for these systems. The method is simple and gentle and is applicable, in principle, to cells while undergoing culture. The proposed method of recovery has the potential of preserving the viability of cultured cells so that it may be possible to reuse them several times for product formation and recovery.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43CA056219-01A1
Application #
3493008
Study Section
Special Emphasis Panel (SSS (B3))
Project Start
1992-07-01
Project End
1993-03-31
Budget Start
1992-07-01
Budget End
1993-03-31
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Symbiotech, Inc.
Department
Type
DUNS #
City
Wallingford
State
CT
Country
United States
Zip Code
06492