Abstract

A Taxol prodrug derivative will be prepared. This compound will be tested for its differential cytotoxicity compared to Taxol; and for its ability to be enzymatically activated. The cytotoxicity of the prodrug in combination with a monoclonal-antibody enzyme conjugate in the presence of targeted and non-targeted cells will also be examined.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43CA059141-01
Application #
3493313
Study Section
Special Emphasis Panel (SSS (B5))
Project Start
1993-02-01
Project End
1993-07-31
Budget Start
1993-02-01
Budget End
1993-07-31
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
Hawaii Biotech, Inc.
Department
Type
DUNS #
113226823
City
Aiea
State
HI
Country
United States
Zip Code
96701