The opioid crisis is the deadliest drug epidemic in American history and new approaches are needed. One novel approach includes predicting likelihood of opioid use disorder (OUD) treatment retention by assessing someone?s risk of early departure from treatment. Current methods to improve treatment retention rely on providers using their intuition to identify when an individual is at risk of leaving treatment early in order to intervene, which often happens too late. Mobile health and machine learning predictive analytics offer a new opportunity to personalize OUD treatment, improve retention in OUD care, and mitigate the risk of relapse and overdose episodes. Project Motivate will combine physiological and behavioral data from disparate sources in order to predict when an individual is at risk of early departure from OUD treatment. This data will be displayed in a user-friendly manner so that providers can more effectively support patients to remain in treatment with timely intervention and responses.

Public Health Relevance

Early departure from opioid use disorder treatment programs is common, with early termination rates over 50% for many opioid use disorder treatments, putting individuals at an increased risk of relapsing, overdose and death. Using physiological monitoring tools to predict the likelihood that someone is at risk of early departure from opioid use disorder treatment due to worsening symptoms and/or cravings will allow for proactive interventions that will improve treatment retention. Making an impact here will not only save lives, but it will also lower medical costs, municipal emergency response costs, recidivism, workplace accidents, lost workplace productivity and costs to families.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43DA051279-01
Application #
10013066
Study Section
Special Emphasis Panel (ZDA1)
Program Officer
Angelone, Leonardo Maria
Project Start
2020-08-01
Project End
2021-01-31
Budget Start
2020-08-01
Budget End
2021-01-31
Support Year
1
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Biomotivate, LLC
Department
Type
DUNS #
081362486
City
Pittsburgh
State
PA
Country
United States
Zip Code
15222